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Table 1 Differences in clinical course of mild/moderately severe and severe AP

From: The clinical value of adipokines in predicting the severity and outcome of acute pancreatitis

 

Mild and moderately severe AP

Severe AP

P value*

 

(n = 82)

(n = 20)

 

Age

55.90 ± 19.02

55.00 ± 14.20

0.814

Sex

 Male (%)

38 (46.3)

12 (60.0)

 

 Female (%)

44 (53.7)

8 (40.0)

 

BMI

27.99 ± 7.54

31.07 ± 10.02

0.041

Adiponectin μg/ml (1st day)

11.10 ± 9.58

7.91 ± 10.07

0.446

Adiponectin μg/ml (3rd day)

10.04 ± 9.14

8.64 ± 6.44

0.870

Leptin ng/ml (1st day)

7.21 ± 11.83

4.17 ± 8.14

0.397

Leptin ng/ml (3rd day)

2.33 ± 3.85

0.84 ± 6.03

0.533

Visfatin ng/ml (1st day)

4.15 ± 5.45

5.42 ± 4.74

0.179

Visfatin ng/ml (3rd day)

2.94 ± 4.58

7.34 ± 5.68

0.059

IL-6 pg/ml (1st day)

133.00 ± 350.47

635.95 ± 634.45

0.000

IL-6 pg/ml (3rd day)

94.97 ± 323.86

545.31 ± 574.17

0.000

Resistin ng/ml (1st day)

10.70 ± 8.65

20.20 ± 31.75

0.000

Resistin ng/ml (3rd day)

11.67 ± 14.87

40.75 ± 28.27

0.000

CRP mg/ml (1st day)

9.54 ± 64.79

16.15 ± 74.86

0.220

CRP mg/ml (3rd day)

180.30 ± 224.87

377.13 ± 91.39

0.000

SOFA (1st day) (score)

1 ± 2

3 ± 3

0.000

SOFA (3rd day) (score)

1 ± 2

4 ± 2

0.000

MCTSI (score)

6 ± 4

8 ± 2

0.000

Pancreatic necrosis (%)

40 (48.8)

20 (100)

0.000

Peripancreatic necrosis volume (ml) (n)

31.50 ± 518.50 (48)

731.00 ± 2141.50 (19)

0.000

Need for surgery (%)

2 (2.4)

8 (40.0)

0.000

Hospital stay (d)

11.00 ± 7.00

30 ± 22.75

0.000

Number of deaths (%)

0 (0.0)

5 (25.0)

0.000

  1. Abbreviations: AP Acute Pancreatis, BMI Body Mass Index, IL-6 Interleukin-6, CRP C-Reactive Protein, SOFA The Sequential Organ Failure Assessment score, MCTSI Modified Computed Tomography Severity Index
  2. Age was expressed as mean ± standard deviation (SD); sex, pancreatic necrosis, need for surgery and number of deaths by percents, other variables - as median ± interquartile ranges (IQR)
  3. *Significant in bold