From: Distribution and clinical significance of hepatitis B virus genotypes in Pakistan
Characteristics | Genotype A | Genotype D | Genotype A + D | Sig. | |
---|---|---|---|---|---|
Number of patients (%) | 43 (11.2) | 279 (72.7) | 62 (16.1) | Â | |
Age (Mean ± SD) | 32.4 ± 11.7 | 34.1 ± 12.1 | 35.1 ± 12.8 | NSa | |
Gender (M/F) | 32/11 | 202/77 | 40/22 | NSb | |
Immune Control (N = 56) | normal ALT, HBeAg negative, anti HBe positive, low viral load | 7 (16.3 %) | 36 (12.9 %) | 13 (21.0 %) | NSb |
Immune Tolerant (N = 89) | normal ALT, HBeAg positive, anti HBe negative, high viral load | 10 (23.2 %) | 67 (24.0 %) | 12 (19.3 %) | NSb |
Immune Clearance (N = 153) | elevated ALT, HBeAg positive, high viral load | 15 (34.9 %) | 112 (40.1 %) | 26 (41.9 %) | NSb |
Immune Escape (N = 86) | Normal or elevated ALT, HBeAg negative, anti HBe positive, High HBV DNA, | 11 (25.6 %) | 64 (22.9 %) | 11 (17.7 %) | NSb |