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Table 1 Results from the single SNP association analysis for SNPs with a two-sided p value < 0.01 from Fisher’s exact test in the initial sample or in one of the sex-specific subgroups

From: Male-specific association between MT-ND4 11719 A/G polymorphism and ulcerative colitis: a mitochondria-wide genetic association study

mtSNPa BPb A1c A2d Subsample Initial analysis Replication Combinedg
p ORe A1c frequency p ORe A1 frequency p ORe
Cases Ctrlsf Cases Ctrlsf
rs2853495 11719 G A Total 0.007 1.22 [1.06; 1.40] 0.528 0.478 0.011 1.17 [1.04; 1.31] 0.525 0.486 1.92110−4 1.19 [1.09; 1.30]
Males 0.002 1.40 [1.13; 1.73] 0.562 0.479 0.002 1.32 [1.10; 1.57] 0.551 0.482 1.51210−5 1.35 [1.18; 1.55]
Females 0.328 1.10 [0.91; 1.34] 0.502 0.477
rs3899498 13368 A G Total 0.005 0.71 [0.56; 0.91] 0.085 0.115 0.334 0.90 [0.74; 1.10] 0.091 0.100 1.01210−2 0.82 [0.70; 0.95]
Males 0.126 0.75 [0.53; 1.07] 0.090 0.117
Females 0.026 0.68 [0.49; 0.96] 0.080 0.113
  1. aMitochondrial single nucleotide polymorphism; bBase-pair position according to UCSC version hg19; cEffect allele; dSecond allele; eOdds ratio with 95 % confidence interval; fControls; gCombined analysis of initial and replication data