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Table 3 Univariable analysis for PHG in patients with liver cirrhosis

From: Portal hypertensive gastropathy as a prognostic index in patients with liver cirrhosis

Variables, N (%) No PHG Mild PHG Severe PHG P value
N = 50 (8.5 %) N = 411 (70 %) N = 126 (21.5 %)
Age (years), Median (Interquartile range) 52 (43–60.25) 52 (46–60) 51 (45–56) 0.24
Sex     0.001
Male 30 (60 %) 324 (78.8 %) 108 (85.7 %)
Female 20 (40 %) 87 (21.2 %) 18 (14.3 %)
Etiology     <0.001
Alcohol 20 (40 %) 284 (69.1 %) 106 (84.1 %)
HBV 26 (52 %) 99 (24.1 %) 17 (13.5 %)
HCV 4 (8 %) 27 (6.6 %) 3 (2.4 %)
Non-alcoholic 0 (0 %) 1 (0.2 %) 1 (0 %)
Child-Pugh classification     <0.001
Class A 37 (74 %) 197 (47.9 %) 49 (38.9 %)
Class B 12 (24 %) 169 (41.1 %) 53 (42.1 %)
Class C 1 (2 %) 45 (10.9 %) 24 (19 %)
HVPG (mmHg), Median (Interquartile range) 9.2 (7.2–16.7) 14.6 (10.1–19.3) 17.3 (12.3–21.5) <0.001
MELD score 6.00 (6.00–8.07) 9.41 (6.00–12.85) 10.64 (6.94–14.73) <0.001
Albumin (g/dL) 3.7 (3.0–4.1) 3.3 (2.8–3.8) 3.2 (2.8–3.6) 0.001
Total bilirubin (mg/dL) 0.9 (0.6–1.2) 1.4 (0.8–2.5) 1.9 (1.0–4.3) <0.001
Platelet count (x 103/mL) 141.5 (94.8–214.3) 103 (75–156) 104 (66.8–167) 0.004
Prothrombin time (INR) 1.12 (1.04–1.32) 1.26 (1.11–1.44) 1.29 (1.15–1.49) <0.001
Survival 46 (92 %) 327 (79.6 %) 95 (75.4 %)  
HCC 5 (10 %) 43 (10.5 %) 6 (4.8 %)  
  1. HVPG, Severe PHG vs Mild PHG: P = 0.001, Severe PHG vs No PHG: P < 0.001, Mild PHG vs No PHG: P < 0.001
  2. MELD score, Severe PHG vs Mild PHG: P = 0.015, Severe PHG vs No PHG: P < 0.001, Mild PHG vs No PHG: P < 0.001
  3. Albumin, Severe PHG vs Mild PHG: P = 0.18, Severe PHG vs No PHG: P < 0.001, Mild PHG vs No PHG: P = 0.002
  4. Total bilirubin, Severe PHG vs Mild PHG: P < 0.001, Severe PHG vs No PHG: P < 0.001, Mild PHG vs No PHG: P < 0.001
  5. Platelet, Severe PHG vs Mild PHG: P = 0.49, Severe PHG vs No PHG: P = 0.004, Mild PHG vs No PHG: P = 0.001
  6. INR, Severe PHG vs Mild PHG: P = 0.14, Severe PHG vs No PHG: P < 0.001, Mild PHG vs No PHG: P < 0.001
  7. Survival, Severe PHG vs Mild PHG: P = 0.08, Severe PHG vs No PHG: P < 0.001, Mild PHG vs No PHG: P = 0.008
  8. HCC, severe PHG vs Mild PHG: P = 0.63, Severe PHG vs No PHG: P = 0.34, Mild PHG vs No PHG: P = 0.32
  9. N number, HBV hepatitis B virus, HCV hepatitis C virus, PHG portal hypertensive gastropathy, HVPG hepatic vein pressure gradient, MELD model for end-stage liver disease, INR international normalized ratio, SD standard deviation, HCC hepatocellular carcinoma