Table 1 Demographic and clinical characteristics of the patients with G-NENs (n = 135)
From: Surgical treatment and prognosis of gastric neuroendocrine neoplasms: a single-center experience
Variables | NET G1 (n = 39, %) | NET G2 (n = 7, %) | NEC G3 (n = 69, %) | MANEC (n = 20, %) | P value |
|---|---|---|---|---|---|
Gender | <0.001 | ||||
Male | 19 (48.7) | 5 (71.4) | 54 (78.3) | 20 (100.0) | |
Female | 20 (51.3) | 2 (28.6) | 15 (21.7) | 0 (0.0) | |
Age, y | 53.3 ± 13.0 | 47.0 ± 13.1 | 61.0 ± 10.3 | 62.2 ± 10.5 | <0.001 |
Lesion diameter, cm | 1.2 ± 0.9 | 2.4 ± 1.8 | 5.2 ± 1.8 | 4.7 ± 3.1 | <0.001 |
Hospital stay, days | 10.7 ± 4.9 | 14.9 ± 5.6 | 16.0 ± 5.0 | 17.1 ± 5.5 | <0.001 |
Tumor location | <0.001 | ||||
U | 7 (17.9) | 2 (28.6) | 36 (52.2) | 9 (45.0) | |
M | 29 (74.4) | 3 (42.9) | 11 (15.9) | 2 (10.0) | |
L | 3 (7.7) | 2 (28.6) | 22 (31.9) | 9 (45.0) | |
Number of lesions | 0.245 | ||||
Multiple | 8 (20.5) | 1 (14.3) | 1 (1.4) | 0 (0.0) | |
single | 31 (79.5) | 6 (85.7) | 68 (98.6) | 20 (100.0) | |
Mucosal ulcer | <0.001 | ||||
Present | 10 (25.6) | 7 (100.0) | 68 (98.6) | 19 (95.0) | |
Absent | 29 (74.4) | 0 (0.0) | 1 (1.4) | 1 (5.0) | |
Co-morbidity* | 0.042 | ||||
Present | 5 (12.8) | 2 (28.6) | 14 (20.3) | 9 (45.0) | |
Absent | 34 (87.2) | 5 (71.4) | 55 (79.7) | 11 (55.0) | |
Anemia | 0.643 | ||||
Yes | 5 (12.8) | 2 (28.6) | 9 (13.0) | 3 (15.0) | |
No | 34 (87.2) | 5 (71.4) | 60 (87.0) | 17 (85.0) | |
Hemoglobin level, g/L | 127.8 ± 20.5 | 113.0 ± 20.6 | 124.1 ± 25.5 | 126.0 ± 20.3 | 0.463 |
NLR | 2.5 ± 1.5 | 2.3 ± 1.6 | 3.0 ± 1.2 | 3.1 ± 2.1 | 0.197 |
A/G ratio | 1.5 ± 0.3 | 1.5 ± 0.2 | 1.5 ± 0.3 | 1.6 ± 0.3 | 0.581 |
Tumor markers | |||||
CEA↑ | 2 (5.1) | 0 (0.0) | 13 (18.8) | 3 (15.0) | 0.194 |
AFP↑ | 0 (0.0) | 0 (0.0) | 3 (4.3) | 0 (0.0) | 0.638 |
CA19-9↑ | 1 (2.6) | 0 (0.0) | 8 (11.6) | 2 (10.0) | 0.354 |
CA125↑ | 1 (2.6) | 0 (0.0) | 2 (2.9) | 0 (0.0) | 1.000 |
CA72-4↑ | 0 (0.0) | 0 (0.0) | 2 (2.9) | 2 (10.0) | 0.217 |