From: Clinical efficacy of adalimumab in Crohn’s disease: a real practice observational study in Japan
Basic characteristic | Risk factor | Clinical remission (last examination) | Endoscopy (last examination) | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Patient | Gender | Age (years) | Disease duration (months) | Disease location | Previous IFX | Time to ADA after resection (days) | Smoking | Penetrating disease | Previous resection | Disease duration (<10 years) | Numbers of risk factors | Time to last examination (months) | Remission | Time to Endoscopy(months) | Rutgeerts score | Mucosal healing |
1 | M | 33 | 153 | Ileocolonic | ○ | 43 | × | ○ | ○ | × | 2 | 48 | ○ | 20 | i0 | ○ |
2 | M | 32 | 77 | Ileocolonic | ○ | 18 | ○ | ○ | ○ | ○ | 4 | 50 | ○ | 44 | i4 | × |
3 | M | 38 | 96 | Ileocolonic | × | 23 | ○ | ○ | × | ○ | 3 | 49 | ○ | 47 | i0 | ○ |
4 | M | 30 | 178 | Ileo | ○ | 57 | × | ○ | ○ | × | 2 | 46 | × | 37 | i3 | × |
5 | M | 29 | 3 | Ileocolonic | × | 40 | ○ | × | × | ○ | 2 | 40 | ○ | 28 | i2 | × |
6 | M | 50 | 276 | Ileo | × | 49 | × | × | ○ | × | 1 | 32 | ○ | 23 | i0 | ○ |
7 | M | 19 | 8 | Ileocolonic | × | 15 | ○ | × | × | ○ | 2 | 38 | ○ | 22 | i0 | ○ |
8 | M | 50 | 480 | Ileocolonic | ○ | 23 | × | ○ | ○ | × | 2 | 38 | ○ | 38 | i1 | ○ |
9 | M | 34 | 180 | Ileo | ○ | 60 | ○ | × | ○ | × | 2 | 31 | ○ | 8 | i0 | ○ |
10 | M | 33 | 120 | Ileo | × | 240 | × | ○ | × | ○ | 2 | 29 | ○ | 28 | i2 | × |
11 | M | 43 | 204 | Ileocolonic | × | 73 | × | ○ | ○ | × | 2 | 32 | ○ | - | - | - |
12 | M | 47 | 36 | Ileocolonic | × | 53 | × | ○ | ○ | ○ | 3 | 24 | ○ | - | - | - |
13 | M | 23 | 18 | Ileocolonic | × | 22 | × | ○ | × | ○ | 2 | 15 | ○ | 8 | i0 | ○ |
14 | F | 45 | 396 | Ileocolonic | × | 82 | × | ○ | ○ | × | 2 | 24 | ○ | 24 | i3 | × |
15 | M | 27 | 3 | Ileocolonic | × | 10 | × | × | × | ○ | 1 | 16 | ○ | 15 | i0 | ○ |
16 | F | 31 | 18 | Ileocolonic | × | 38 | × | ○ | × | ○ | 2 | 12 | ○ | 12 | i0 | ○ |
Total | M/F: 14/2 | 35.3 | 140.4 | 4/12 | 31.3 % (5/16) | 52.9 | 31.3 % (5/16) | 68.8 % (11/16) | 56.3 % (9/16) | 56.3 % (9/16) | 2.1 | 32.3 | 93.8 % (15/16) | 25.3 | - | 64.3 % (9/14) |