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Table 4 Impact of PPI intake on the type of bacteria of the duodenal aspirates in relation to the presence of IBS or not

From: Small intestinal bacterial overgrowth is associated with irritable bowel syndrome and is independent of proton pump inhibitor usage

  Type of bacteria No PPI intake (%) PPI intake (%) p
SIBO without IBS (n = 65) Escherichia coli 11 (20.7) 2 (16.7)  
  Klebsiella pneumoniae 11 (20.7) 2 (16.7)  
  Enterobacter cloacae 7 (13.2) 0 (0)  
  Staphylococcus aureus 6 (11.3) 2 (16.7)  
  Enterococcus faecalis 3 (5.7) 1 (8.3)  
  Pseudomonas aeruginosa 3 (5.7) 0 (0)  
  Enterobacter aerogenes 2 (3.8) 3 (25.0) 0.644
  Proteus mirabilis 1 (1.9) 0 (0)  
  Serratia marscecens 2 (3.8) 0 (0)  
  Acinetobacter baumannii 2 (3.8) 0 (0)  
  Stenotrophomonas maltophilia 1 (1.9) 0 (0)  
  Citrobacter freundii 0 (0) 1 (8.3)  
SIBO with IBS (n = 93) Escherichia coli 22 (31.4) 6 (26.1)  
  Enterobacter cloacae 9 (12.9) 0 (0)  
  Klebsiella pneumoniae 8 (11.4) 6 (26.1)  
  Enterococcus faecium 4 (5.7) 0 (0)  
  Staphylococcus aureus 3 (4.3) 1 (4.3) 0.125
  Enterococcus faecalis 3 (4.3) 2 (8.7)  
  Enterobacter aerogenes 3 (4.3) 2 (8.7)  
  Klebsiella oxytoca 3 (4.3) 1 (4.3)  
  Pseudomonas aeruginosa 3 (4.3) 0 (0)  
  Acinetobacter baumannii 2 (2.9) 0 (0)  
  Serratia marscecens 1 (1.4) 2 (8.7)  
  1. P values indicate differences in the distribution of bacterial species between patients wihout and with history of PPI intake