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Table 4 Impact of PPI intake on the type of bacteria of the duodenal aspirates in relation to the presence of IBS or not

From: Small intestinal bacterial overgrowth is associated with irritable bowel syndrome and is independent of proton pump inhibitor usage

 

Type of bacteria

No PPI intake (%)

PPI intake (%)

p

SIBO without IBS (n = 65)

Escherichia coli

11 (20.7)

2 (16.7)

 
 

Klebsiella pneumoniae

11 (20.7)

2 (16.7)

 
 

Enterobacter cloacae

7 (13.2)

0 (0)

 
 

Staphylococcus aureus

6 (11.3)

2 (16.7)

 
 

Enterococcus faecalis

3 (5.7)

1 (8.3)

 
 

Pseudomonas aeruginosa

3 (5.7)

0 (0)

 
 

Enterobacter aerogenes

2 (3.8)

3 (25.0)

0.644

 

Proteus mirabilis

1 (1.9)

0 (0)

 
 

Serratia marscecens

2 (3.8)

0 (0)

 
 

Acinetobacter baumannii

2 (3.8)

0 (0)

 
 

Stenotrophomonas maltophilia

1 (1.9)

0 (0)

 
 

Citrobacter freundii

0 (0)

1 (8.3)

 

SIBO with IBS (n = 93)

Escherichia coli

22 (31.4)

6 (26.1)

 
 

Enterobacter cloacae

9 (12.9)

0 (0)

 
 

Klebsiella pneumoniae

8 (11.4)

6 (26.1)

 
 

Enterococcus faecium

4 (5.7)

0 (0)

 
 

Staphylococcus aureus

3 (4.3)

1 (4.3)

0.125

 

Enterococcus faecalis

3 (4.3)

2 (8.7)

 
 

Enterobacter aerogenes

3 (4.3)

2 (8.7)

 
 

Klebsiella oxytoca

3 (4.3)

1 (4.3)

 
 

Pseudomonas aeruginosa

3 (4.3)

0 (0)

 
 

Acinetobacter baumannii

2 (2.9)

0 (0)

 
 

Serratia marscecens

1 (1.4)

2 (8.7)

 
  1. P values indicate differences in the distribution of bacterial species between patients wihout and with history of PPI intake