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Table 2 Liver elasticity, serum data, and serum markers, measured before and after biliary drainage

From: Liver elasticity measurement before and after biliary drainage in patients with obstructive jaundice: a prospective cohort studya prospective cohort study

  Day 0 (n = 20) Day 2 (n = 20) Day 7 (n = 20) > Day 7 (n = 10) P *
TE (kPa) 12.1 ± 0.9 9.2 ± 0.8 7.6 ± 0.6 6.7 ± 0.9 <0.001
VTQ-L (m/s) 2.23 ± 0.10 1.76 ± 0.09 1.53 ± 0.08 1.28 ± 0.07 <0.001
VTQ-R (m/s) 1.85 ± 0.10 1.50 ± 0.05 1.30 ± 0.05 1.16 ± 0.08 <0.001
T-Bil (mg/dl) 11.9 ± 1.5 8.0 ± 1.4 4.7 ± 1.0 1.0 ± 0.1 <0.001
AST (U/L) 209.8 ± 28.8 129.4 ± 23.0 66.8 ± 7.7 34.3 ± 6.6 <0.001
γ-GT (U/L) 1123.7 ± 166.2 839.0 ± 123.2 416.6 ± 63.7 202.4 ± 51.1 <0.001
ALP (U/L) 2,325.1 ± 217 1,987.9 ± 198.2 1,258.2 ± 126.5 682.8 ± 164.1 <0.001
Plt (×104/μl) 25.9 ± 1.3 26.3 ± 1.5 29.2 ± 1.7 24.2 ± 1.7 NS
γ-globulin (g/dl) 1.20 ± 0.05   1.14 ± 0.06 1.09 ± 0.09 0.011
T-cho (mg/dl) 243.7 ± 17.5   186.5 ± 13.8 172.9 ± 12.4 <0.001
Hyaluronic acid (ng/ml) 324.2 ± 61.4   199.9 ± 41.6 118.0 ± 25.7 0.002
P-III-P (U/ml) 1.40 ± 0.10   1.14 ± 0.07 0.09 ± 0.08 0.004
IV collagen (ng/ml) 7.9 ± 0.9   7.2 ± 0.6 6.5 ± 0.8 NS
Forns' Index 6.98 ± 0.41   6.76 ± 0.42 6.56 ± 0.46 NS
Fibro Index 1.69 ± 0.18   0.73 ± 0.13 0.61 ± 0.25 <0.001
APRI 2.60 ± 0.40   0.79 ± 0.15 0.43 ± 0.11 <0.001
  1. TE Transient Elastography, VTQ-L Virtual Touch™ quantification-Left lobe, VTQ-R Virtual Touch™ quantification-Right lobe, T-Bil total bilirubin, AST aspartate aminotransferase, γ-GT gamma-glutamyl transpeptidase, ALP alkaline phosphatase, Plt platelet, T-cho total cholesterol, P-III-P procollagen-III-peptide, IV collagen, type IV collagen 7S, APRI aspartate aminotransferase-to-platelet ratio index
  2. All data are shown as means ± SE; *in comparison with Day 0 and Day 7