Table 2 Liver elasticity, serum data, and serum markers, measured before and after biliary drainage

TE (kPa)

12.1 ± 0.9

9.2 ± 0.8

7.6 ± 0.6

6.7 ± 0.9

<0.001

VTQ-L (m/s)

2.23 ± 0.10

1.76 ± 0.09

1.53 ± 0.08

1.28 ± 0.07

<0.001

VTQ-R (m/s)

1.85 ± 0.10

1.50 ± 0.05

1.30 ± 0.05

1.16 ± 0.08

<0.001

T-Bil (mg/dl)

11.9 ± 1.5

8.0 ± 1.4

4.7 ± 1.0

1.0 ± 0.1

<0.001

AST (U/L)

209.8 ± 28.8

129.4 ± 23.0

66.8 ± 7.7

34.3 ± 6.6

<0.001

γ-GT (U/L)

1123.7 ± 166.2

839.0 ± 123.2

416.6 ± 63.7

202.4 ± 51.1

<0.001

ALP (U/L)

2,325.1 ± 217

1,987.9 ± 198.2

1,258.2 ± 126.5

682.8 ± 164.1

<0.001

Plt (×10⁴/μl)

25.9 ± 1.3

26.3 ± 1.5

29.2 ± 1.7

24.2 ± 1.7

NS

γ-globulin (g/dl)

1.20 ± 0.05

1.14 ± 0.06

1.09 ± 0.09

0.011

T-cho (mg/dl)

243.7 ± 17.5

186.5 ± 13.8

172.9 ± 12.4

<0.001

Hyaluronic acid (ng/ml)

324.2 ± 61.4

199.9 ± 41.6

118.0 ± 25.7

0.002

P-III-P (U/ml)

1.40 ± 0.10

1.14 ± 0.07

0.09 ± 0.08

0.004

IV collagen (ng/ml)

7.9 ± 0.9

7.2 ± 0.6

6.5 ± 0.8

NS

Forns' Index

6.98 ± 0.41

6.76 ± 0.42

6.56 ± 0.46

NS

Fibro Index

1.69 ± 0.18

0.73 ± 0.13

0.61 ± 0.25

<0.001

APRI

2.60 ± 0.40

0.79 ± 0.15

0.43 ± 0.11

<0.001