Fig. 3

Changes in Serum Markers of Liver Fibrosis. a Hyaluronic acid (HA), b procollagen-III-peptide (P-III-P), c type IV collagen 7S (IV collagen), d Forns’ Index, e Fibro Index, and (f) APRI were measured, before and after biliary drainage. HA, P-III-P, Fibro Index, and APRI were elevated before drainage and decreased significantly at Day 7 after biliary drainage. IV collagen and Forns’ Index were elevated before drainage and tended to decrease at Day 7 after biliary drainage. In 10 patients who underwent assessment after Day 7, all the markers decreased. Data are shown as means ± SE; ** P < 0.01 versus Day 0