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Table 2 Relationship between Cyr-61/COX-2 protein levels and clinicopathologic features of patients with gastric cancer

From: Prognostic significance of expression of cysteine-rich 61 and cyclooxygenase-2 in gastric cancer

Characteristic Number Cyr-61 COX-2
High Low p High Low p
Diameter of tumor     0.190    0.003
  ≥4 58 38 20   42 16  
  <4 24 12 12   9 15  
Infiltration depth     0.027    <0.001
 T1 4 1 3   1 3  
 T2 24 10 14   7 17  
 T3 25 17 8   20 5  
 T4 29 22 7   23 6  
Lymph node metastasis     0.001    < 0.001
 Yes 56 41 15   42 14  
 No 26 9 17   9 17  
Distance metastasis     0.045    0.017
 Yes 23 18 5   19 4  
 No 59 32 27   32 27  
Histological grade     0.031    0.015
 I 17 6 11   7 10  
 II 22 13 9   11 11  
 III 43 31 12   33 10  
Gender     0.752    0.971
 Male 58 36 22   36 22  
 Female 24 14 10   15 9  
TNM stage     0.009    < 0.001
 I 19 6 13   3 16  
 II 13 7 6   8 5  
 III 25 17 8   20 5  
 IV 25 20 5   20 5  
  1. Abbreviations: Cyr-61 cysteine-rich 61, COX-2 cyclooxygenase-2, TNM tumour node metastasis