Table 2 Relationship between Cyr-61/COX-2 protein levels and clinicopathologic features of patients with gastric cancer
From: Prognostic significance of expression of cysteine-rich 61 and cyclooxygenase-2 in gastric cancer
Characteristic | Number | Cyr-61 | COX-2 | ||||
|---|---|---|---|---|---|---|---|
High | Low | p | High | Low | p | ||
Diameter of tumor | 0.190 | 0.003 | |||||
≥4 | 58 | 38 | 20 | 42 | 16 | ||
<4 | 24 | 12 | 12 | 9 | 15 | ||
Infiltration depth | 0.027 | <0.001 | |||||
T1 | 4 | 1 | 3 | 1 | 3 | ||
T2 | 24 | 10 | 14 | 7 | 17 | ||
T3 | 25 | 17 | 8 | 20 | 5 | ||
T4 | 29 | 22 | 7 | 23 | 6 | ||
Lymph node metastasis | 0.001 | < 0.001 | |||||
Yes | 56 | 41 | 15 | 42 | 14 | ||
No | 26 | 9 | 17 | 9 | 17 | ||
Distance metastasis | 0.045 | 0.017 | |||||
Yes | 23 | 18 | 5 | 19 | 4 | ||
No | 59 | 32 | 27 | 32 | 27 | ||
Histological grade | 0.031 | 0.015 | |||||
I | 17 | 6 | 11 | 7 | 10 | ||
II | 22 | 13 | 9 | 11 | 11 | ||
III | 43 | 31 | 12 | 33 | 10 | ||
Gender | 0.752 | 0.971 | |||||
Male | 58 | 36 | 22 | 36 | 22 | ||
Female | 24 | 14 | 10 | 15 | 9 | ||
TNM stage | 0.009 | < 0.001 | |||||
I | 19 | 6 | 13 | 3 | 16 | ||
II | 13 | 7 | 6 | 8 | 5 | ||
III | 25 | 17 | 8 | 20 | 5 | ||
IV | 25 | 20 | 5 | 20 | 5 | ||