| |
Week
|
MF
|
HFCD
|
MF + DEN
|
HFCD + DEN
|
|---|
|
Mice with positive findings, n (%)
|
12
|
0
|
0
|
0
|
0
|
|
16
|
0
|
0
|
0
|
1/5 (20 %)
|
|
20
|
0
|
1/5 (20 %)
|
0
|
5/5 (100 %)
|
|
24
|
0
|
0
|
1/5 (20 %)
|
5/5 (100 %)
|
|
Tumor number
|
12
|
0
|
0
|
0
|
0
|
|
16
|
0
|
0
|
0
|
5
|
|
20
|
0
|
6
|
0
|
10.0 ± 5.4
|
|
24
|
0
|
0
|
1
|
8.8 ± 5.4
|
|
Tumor size (mm)
|
12
| | | | |
|
16
| | | |
0.6 ± 0.4
|
|
20
| |
0.8 ± 0.2
| |
1.6 ± 0.8
|
|
24
| | |
2.2
|
2.9 ± 2.8
|
- Data are shown as the mean ± standard deviation. Data in bold indicate a significant difference (p < 0.05) between the standard diet (MF) group and the other groups for each month. HFCD high-fat choline-deficient diet, DEN diethylnitrosamine
