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Table 3 Nonalcoholic fatty liver disease activity score (NAS)

From: Development of a novel mouse model of hepatocellular carcinoma with nonalcoholic steatohepatitis using a high-fat, choline-deficient diet and intraperitoneal injection of diethylnitrosamine

 

Week

MF

HFCD

MF + DEN

HFCD + DEN

NAS

4

0

0.6 ± 0.9

0.6 ± 0.6

1.3 ± 0.5

8

0

0.8 ± 0.8

0.4 ± 0.6

1.2 ± 1.6

12

0

2.6 ± 1.7

1 ± 0

3 ± 2.0

16

0.2 ± 0.5

4.6 ± 2.2

1 ± 0

5.2 ± 1.3

20

0

5.2 ± 0.5

1 ± 0

5.4 ± 0.6

24

0

6.2 ± 0.8

1 ± 0

5.6 ± 0.6

  1. Each group contained five mice. MF standard diet, HFCD high-fat choline-deficient diet, DEN diethylnitrosamine
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BMC Gastroenterology

ISSN: 1471-230X

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