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Table 3 Nonalcoholic fatty liver disease activity score (NAS)

From: Development of a novel mouse model of hepatocellular carcinoma with nonalcoholic steatohepatitis using a high-fat, choline-deficient diet and intraperitoneal injection of diethylnitrosamine

  Week MF HFCD MF + DEN HFCD + DEN
NAS 4 0 0.6 ± 0.9 0.6 ± 0.6 1.3 ± 0.5
8 0 0.8 ± 0.8 0.4 ± 0.6 1.2 ± 1.6
12 0 2.6 ± 1.7 1 ± 0 3 ± 2.0
16 0.2 ± 0.5 4.6 ± 2.2 1 ± 0 5.2 ± 1.3
20 0 5.2 ± 0.5 1 ± 0 5.4 ± 0.6
24 0 6.2 ± 0.8 1 ± 0 5.6 ± 0.6
  1. Each group contained five mice. MF standard diet, HFCD high-fat choline-deficient diet, DEN diethylnitrosamine