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Table 1 Summary of laboratory findings for FBS, CRP, IL-6, TNF-alpha, and adiponectin levels

From: Development of a novel mouse model of hepatocellular carcinoma with nonalcoholic steatohepatitis using a high-fat, choline-deficient diet and intraperitoneal injection of diethylnitrosamine

  Week MF HFCD MF + DEN HFCD + DEN
FBS (mg/dl) 4 211.3 ± 41.7 297.5 ± 24.6 191.0 ± 11.2 282.3 ± 26.5
8 149.6 ± 30.9 174.2 ± 32.9 177.0 ± 64.9 167.6 ± 31.3
12 167.6 ± 41.6 241.6 ± 32.4 152.0 ± 24.2 273.4 ± 31.5
16 109.8 ± 11.4 245.0 ± 46.4 112.8 ± 8.7 189.8 ± 52.5
20 188.4 ± 14.6 263.2 ± 36.0 172.0 ± 36.7 242.0 ± 14.4
24 165.2 ± 23.9 265.2 ± 6.5 205.3 ± 32.5 249.4 ± 24.2
CRP (ng/ml) 4 4552.6 ± 2533.3 3756.8 ± 1366.4 4284.9 ± 2261.0 4915.4 ± 1697.0
8 5803.1 ± 1368.7 13324.9 ± 7100.6 5837.7 ± 2422.0 6568.3 ± 3827.0
12 2412.0 ± 211.8 2505.3 ± 517.7 2465.9 ± 170.5 2427.1 ± 337.3
16 2080.4 ± 756.5 3065.7 ± 1047.4 2801.3 ± 457.0 3002.1 ± 599.5
20 2125.1 ± 306.9 3170.3 ± 711.8 2185.4 ± 256.3 3293.4 ± 416.6
24 2227.6 ± 613.8 3143.3 ± 393.3 2044.0 ± 349.9 3686,7 ± 481.2
IL-6 (pg/ml) 4 0.2 ± 0.3 1.3 ± 1.5 0.3 ± 0.5 0.9 ± 1.3
8 0.5 ± 0.5 1.8 ± 1.5 0.6 ± 0.7 0.9 ± 1.2
12 0.8 ± 0.5 1.1 ± 0.7 1.1 ± 0.8 2.0 ± 1.5
16 1.3 ± 0.6 2.9 ± 1.2 1.2 ± 0.8 0.9 ± 0.2
20 1.6 ± 1.2 1.3 ± 0.8 1.4 ± 0.9 1.6 ± 0.9
24 2.1 ± 1.3 4.2 ± 1.8 2.2 ± 4.5 1.6 ± 0.3
TNF-alpha (pg/ml) 4 N.D. 20.7 ± 28.9 N.D. 6.2 ± 12.0
8 1.8 ± 3.9 270.9 ± 297.5 5.0 ± 7.1 134.6 ± 153.7
12 2.2 ± 2.8 0.4 ± 0.9 0.9 ± 2.0 1.9 ± 3.1
16 0.1 ± 0.1 3.4 ± 4.8 0.1 ± 0.3 N.D.
20 1.2 ± 1.6 2.0 ± 2.2 1.4 ± 1.4 1.4 ± 1.3
24 3.8 ± 6.4 5.8 ± 3.0 3.5 ± 5.2 0.5 ± 1.2
  1. The data are shown as the mean ± standard deviation. Each group contained five mice. FBS fasting blood sugar, CRP C-reactive protein, IL interleukin, TNF-alpha tumor necrosis factor-alpha