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Table 3 Results for the direct head-to-head random effects meta-analysis and network meta-analysis

From: Comparison of the effectiveness of polyethylene glycol with and without electrolytes in constipation: a systematic review and network meta-analysis

Comparison Difference in mean stool frequency (direct) Lower credible limit (direct) Upper credible limit (direct) Tau-sq: between study heterogeneity for direct MA Number of data sets for direct MA Difference in mean stool frequency (NMA) Lower credible limit (NMA) Upper credible limit (NMA) Probability active treatment is better than comparator in NMAa
PEG vs Placebo 1.8 0.2 3.6 2.17 10 1.8 1.0 2.8 100.0 %
PEG + E vs Placebo 2.1 −0.1 4.1 2.09 6 1.9 0.9 3.0 100.0 %
PEG + E vs PEG −0.5 −4.5 3.3 2.81 3 0.1 −1.1 1.2 58.5 %
PEG vs Lactulose       1.8 0.0 3.5 97.6 %
PEG + E vs Lactulose 1.7 −4.2 4.9 3.45 2 1.9 0.2 3.6 98.6 %
PEG vs Serotonin agonist       1.3 −1.0 3.5 87.7 %
PEG + E vs Serotonin agonist       1.4 −0.9 3.7 89.2 %
PEG vs Bulk forming       2.6 −0.8 5.8 93.6 %
PEG + E vs Bulk forming       2.6 −0.5 5.8 95.1 %
  1. NMA network meta-analysis, MA meta-analysis aNote a probability of 50 % equates to no difference between the two therapies
  2. Direct head-to-head random effects meta-analysis was performed when there was two or more published studies