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Table 2 Reasons for discontinuation due to unsatisfactory treatment (intention-to-treat population)

From: Randomized, multicenter study: on-demand versus continuous maintenance treatment with esomeprazole in patients with non-erosive gastroesophageal reflux disease

  Patients [n (%)]
On-demand (n = 301) Continuous (n = 297)
Eligibility criteria not fulfilled 4 (1.3) 6 (2.0)
Adverse events 1 (0.3) 6 (2.0)
Improvement/recovery 0 2 (0.7)
Lost to follow-up 6 (2.0) 7 (2.4)
Protocol non-compliance 2 (0.7) 2 (0.7)
Unsatisfied with symptom control 3 (1.0) 2 (0.7)
Other 3 (1.0) 4 (1.3)
Total 19 (6.3) 29 (9.8)a
  1. aDifference versus on-demand treatment was not significant (P = 0.15)