Table 1 Baseline demographics (intention-to-treat population)
Characteristic | On-demand (n = 301) | Continuous (n = 297) |
|---|---|---|
Men, n (%) | 122 (40.5) | 130 (43.8) |
Women, n (%) | 179 (59.5) | 167 (56.2) |
Ethnicity, n (%) | ||
White | 259 (86.0) | 255 (85.9) |
Black | 14 (4.7) | 10 (3.4) |
Asian | 1 (0.3) | 4 (1.3) |
Othera | 27 (9.0) | 28 (9.4) |
Age (y), mean ± SD | 48.2 ± 13.6 | 47.6 ± 15.1 |
Height (cm), mean ± SD | 167.0 ± 9.1 | 167.0 ± 9.9 |
Weight (kg), mean ± SD | 75.1 ± 14.3 | 75.8 ± 14.7 |
Hiatal hernia, n (%) | 96 (31.9) | 108 (36.4) |
Days with heartburn, n (%) | ||
4 d | 26 (8.6) | 31 (10.4) |
5 d | 55 (18.3) | 46 (15.5) |
6 d | 46 (15.3) | 42 (14.1) |
7 d | 174 (57.8) | 178 (59.9) |
Severity of heartburn, n (%) | ||
Mild | 21 (7.0) | 19 (6.4) |
Moderate | 165 (54.8) | 153 (51.5) |
Severe | 115 (38.2) | 125 (42.1) |
Severity of acid regurgitation, n (%) | ||
None | 82 (27.2) | 63 (21.2) |
Mild | 68 (22.6) | 76 (25.6) |
Moderate | 95 (31.6) | 95 (32.0) |
Severe | 56 (18.6) | 63 (21.2) |
Severity of epigastric pain, n (%) | ||
None | 133 (44.2) | 129 (43.4) |
Mild | 96 (31.9) | 81 (27.3) |
Moderate | 54 (17.9) | 64 (21.5) |
Severe | 18 (6.0) | 23 (7.7) |
Severity of dysphagia, n (%) | ||
None | 265 (85.0) | 255 (85.9) |
Mild | 28 (9.3) | 22 (7.4) |
Moderate | 14 (4.7) | 14 (4.7) |
Severe | 3 (1.0) | 6 (2.0) |
Helicobacter pylori-positive, n (%) | 125 (41.5) | 130 (43.8) |