Fig. 4From: Niclosamide induced cell apoptosis via upregulation of ATF3 and activation of PERK in Hepatocellular carcinoma cellsNiclosamide improved ATF3 and CHOP accumulation in the nucleus. QGY7701 or HepG2 cells were treated with 5 μM niclosamide or equal volume of DMSO in the medium for 24 h. Cells were immunostained using (a) anti-ATF3 antibdy or (b) anti-CHOP as described in Material and methods. The scan bar represented 10 μmBack to article page