|
Age mean ± SD (years)
|
50.2 ± 8.5
|
49.3 ± 7.9
|
-
| |
|
Gender distribution[n(%)]
| | |
-
| |
|
Male
|
34(69.3)
|
34(59.6)
| | |
|
Female
|
15(30.6)
|
23(40.3)
| | |
|
BMI, median (range), kg/m2
|
23 ± 12
|
23 ± 12
|
-
| |
|
No of injection,s median (range)
|
48(24)
|
24(62)
|
0.004
|
1.042 (1.013- 1.072)
|
|
Tolerability, [n(%)]
|
49(100)
|
43(75.4)
|
|
*Adjusted No of injections ,mean ± SEM
|
37.28 ± 1.74
|
35.14 ± 1.63
|
-
| |
|
Viral load median, IU/mL
|
432,210
|
738,902
|
-
| |
|
aAST median (range), μkat/L
|
1.66(4.23)
|
1.28(4.2)
|
-
| |
|
bALT median (range), μkat/L
|
1.78(5.47)
|
2.091(5.62)
|
-
| |
|
Albumin median (range), g/L
|
39 ± 20
|
39 ± 10
|
-
| |
|
Bilirubin median (range), μmol/L
|
15.39 ± 50.44
|
13.6 ± 25.6
|
-
| |
|
Hemoglobin median (range), g/dL
|
13 ± 5.6
|
13.8 ± 4.6
|
-
| |
|
Platelets median (range), 109/L
|
163(236)
|
170(207)
|
-
| |
|
cTLC mean ± SD, 109/μL
|
6.5(1.7)
|
6.5(1.3)
|
-
| |
|
Cholesterol mean ± SD, mmol/L
|
4.1 ± 0.86
|
4.2 ± 0.6
|
-
| |
|
Glucose median (range), mmol/L
|
5.27 ± 3.277
|
5.5 ± 3.1
|
-
| |
|
Insulin median (range), pmol/L
|
79.6 ± 113.2
|
63.5 ± 133.3
|
-
| |
|
dHOMA-IR median (range)
|
2.5 ± 5.71
|
2.16 ± 6.04
|
-
| |
|
eAFP median (range), ng/mL
|
3.5(29.5)
|
8(26.3)
|
0.024
|
0.563 (0.342- 0.928)
|
|
*Adjusted AFP, mean ± SE
|
3.5 ± 0.049
|
3.448 ± 0.045
| | |
|
25-OH Vitamin D mean ± SD, ng/mL
|
27.3 ± 9.2
|
21.07 ± 10.1
|
0.002
|
1.068(1.024-1.115)
|
|
IL28B rs12979860 [n(%)]
| | |
Chi2 = 31.35 p < 0.001
|
|
C/C
|
28(57.1)
|
6(10.5)
|
<0.001
|
11.33(4.09-39.35)
|
|
C/T
|
20(40.8)
|
35(62.4)
| | |
|
T/T
|
1(2)
|
16(28.07)
| | |
|
T allele carriers/ T allele non carriers
|
21/28
|
51/6
|
<0.001
|
0.088(0.032-0.244)
|
|
VDR rs2228570 [n(%)]
| | |
Chi2 = 8.554 p = 0.014
|
|
A/A
|
9(18.3)
|
1(1.7)
|
0.018
|
12.6(1.53-103.4)
|
|
A/G
|
18(36.7)
|
24(42.1)
| | |
|
G/G
|
22(44.8)
|
32(56.1)
| | |
