Skip to main content

Table 3 Rates of SVR in relationship to IL28B rs12979860 and vitamin D related genes polymorphisms

From: Integrative role of vitamin D related and Interleukin-28B genes polymorphism in predicting treatment outcomes of Chronic Hepatitis C

 

SVR

P value

IL28B rs12979860

C/C

C/C

C/T + T/T

C/T + T/T

 

CYP2R1 rs10741657

A allele carrier

Non A carrier

A allele carrier

Non A carrier

 

N(%)

29/33 (87.8 %)

27/37(72.9 %)

22/62(35.4 %)

13/68(19.1 %)

<0.001

VDR rs2228570

A allele carrier

Non A carrier

A allele carrier

Non A carrier

 

N(%)

27/29(93 %)

29/41(70.7 %)

23/66(34.8 %)

12/64(18.7)

<0.001

CYP2R1 & VDR

A allele carrier

Non A carrier

A allele carrier

Non A carrier

 

N(%)

17(100 %)

15/23(65.2 %)

15/30(50 %)

6/35(17 %)

<0.001

  1. The statistical analysis was performed using a chi-squared test for linear trend
  2. IL28B: Interleukin 28 B; SVR: sustained viral response; CYP2R1: cytochrome P-450 family 2, subfamily R; VDR: vitamin D receptor
Back to article page