Table 2 Quality of life in the screened birth cohort

How much have you been tired or fatigued during the last 2 weeks?

1–7

CLDQ-HCV Q1 (AE)

3.60 ± 1.96

4.82 ± 1.70

0.0412

4.82 ± 1.70

How much difficulty have you had with bending, lifting, or stooping in the last 2 weeks?

1–7

CLDQ-HCV Q4 (AE)

5.10 ± 1.85

5.53 ± 1.69

0.37

5.53 ± 1.69

How often during the last 2 weeks have you felt a decreased level of energy?

1–7

CLDQ-HCV Q7 (AE)

3.80 ± 2.10

4.98 ± 1.69

0.0155

4.97 ± 1.69

How often during the last 2 weeks have you felt depressed?

1–7

CLDQ-HCV Q16 (EM)

4.40 ± 2.12

5.88 ± 1.49

0.0144

5.87 ± 1.50

How much of the time during the last 2 weeks have you had problems concentrating?

1–7

CLDQ-HCV Q18 (AE)

4.80 ± 1.75

5.70 ± 1.47

0.0471

5.70 ± 1.47

The following questions are about activities you might do during a typical day. Does your health now limit you in these activities? If so, how much?

Vigorous activities, such as running, lifting heavy objects, participating in strenuous sports

1–3

SF-36 PF01

2.10 ± 0.99

2.13 ± 0.82

0.41

2.13 ± 0.82

Moderate activities, such as moving a table, pushing a vacuum cleaner, bowling, or playing golf

1–3

SF-36 PF02

2.20 ± 1.03

2.60 ± 0.67

0.0122

2.59 ± 0.67

Lifting or carrying groceries

1–3

SF-36 PF03

2.30 ± 0.95

2.67 ± 0.60

0.0450

2.67 ± 0.60

Climbing several flights of stairs

1–3

SF-36 PF04

2.20 ± 0.92

2.47 ± 0.72

0.29

2.47 ± 0.72

Climbing one flight of stairs

1–3

SF-36 PF05

2.20 ± 1.03

2.69 ± 0.60

0.0064

2.68 ± 0.61

Bending, kneeling, or stooping

1–3

SF-36 PF06

2.40 ± 0.84

2.47 ± 0.70

0.65

2.47 ± 0.70

Walking more than a mile

1–3

SF-36 PF07

2.20 ± 0.79

2.46 ± 0.76

0.22

2.46 ± 0.76

Walking several hundred yards

1–3

SF-36 PF08

2.10 ± 0.88

2.66 ± 0.64

0.0195

2.66 ± 0.64

Walking one hundred yards

1–3

SF-36 PF09

2.10 ± 0.99

2.73 ± 0.58

0.0063

2.72 ± 0.59

Bathing or dressing yourself

1–3

SF-36 PF10

2.60 ± 0.84

2.86 ± 0.44

0.10

2.86 ± 0.44

Please indicate how true each statement has been for you during the past 7 days.

I feel fatigued

4–0

FACIT-F HI7 (FS)

2.10 ± 1.45

1.11 ± 1.20

0.0107

1.11 ± 1.20

I feel tired

4–0

FACIT-F An2 (FS)

2.00 ± 1.49

1.25 ± 1.16

0.15

1.25 ± 1.16

I have trouble starting things because I am tired

4–0

FACIT-F An3 (FS)

1.70 ± 1.64

0.80 ± 1.12

0.0148

0.80 ± 1.13

I have energy

0–4

FACIT-F An5 (FS)

1.80 ± 0.63

2.41 ± 1.18

0.0352

2.41 ± 1.18

I need help doing my usual activities

4–0

FACIT-F An14 (FS)

0.80 ± 0.79

0.37 ± 0.86

0.0100

0.37 ± 0.86

Average score

0–100

generic

58.9 ± 32.5

76.3 ± 21.3

0.071

76.2 ± 21.4