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Table 3 Adjusted Risk for 42-Day and One-Year Mortality Stratified by DM, Chronic Kidney Diseases, and Sex

From: Effect of coexisting diabetes mellitus and chronic kidney disease on mortality of cirrhotic patients with esophageal variceal bleeding

  42-day mortality One-year mortality
  Model 1a Model 2b Model 3a Model 4b
  HR 95 % CI P value HR 95 % CI P value HR 95 % CI P value HR 95 % CI P value
All patients             
 Non-DM & CKD Ref.       Ref.      
 Only DM 0.72 0.50–1.02 0.062     0.80 0.64–1.02 0.066    
 Only CKD 1.25 0.62–2.52 0.541     1.07 0.65–1.76 0.801    
 DM + CKD 1.99 1.03–3.84 0.042     1.84 1.14–2.98 0.012    
P for DM × CKD interaction 0.100      0.028    
Women           
 Non-DM & CKD    Ref.      Ref.   
 Only DM    1.11 0.56–2.21 0.772    0.77 0.49–1.21 0.260
 Only CKD    3.40 0.75–15.48 0.113    1.30 0.39–4.28 0.672
 DM + CKD    4.03 1.40–11.59 0.010    2.84 1.31–6.14 0.008
Men           
 Non-DM & CKD    2.00 1.14–3.52 0.016    1.61 1.13–2.29 0.009
 Only DM    1.25 0.67–2.32 0.487    1.32 0.90–1.92 0.154
 Only CKD    2.02 0.83–4.94 0.123    1.64 0.90–2.98 0.108
 DM + CKD    2.93 1.14–7.57 0.026    2.42 1.28–4.57 0.007
P for gender × diseases interaction    0.920    0.559
  1. CI confidence interval, CKD chronic kidney disease, DM diabetes mellitus, HR hazard ratio, Ref reference
  2. aAdjusted for sex, age, comorbidities, etiology of cirrhosis, complications of cirrhosis, low income and urbanization
  3. bAdjusted for age, comorbidities, etiology of cirrhosis, complications of cirrhosis, low income and urbanization