Table 4 Risks of first drug prescription according to first level of Anatomical Therapeutic Chemical (ATC) Classification after date of diagnosis in CD subjects compared to matched references, stratified by first outcome occurrence (30–365 days after the index date/>365 days after the index date)a
First outcome occurrence | 30–365 days | >1 year after index dateb | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
ATC codesb | REFERENCES | CD | HR (95 % CI) | REFERENCES | CD | HR (95 % CI) | ||||
n | py | n | py | n | py | n | py | |||
A | 131 | 5320 | 140 | 1129 | 4.70 (3.66–6.04) | 406 | 32774 | 158 | 6926 | 1.78 (1.45–2.17) |
B | 48 | 5543 | 91 | 1534 | 6.35 (2.93–13.75) | 210 | 34991 | 102 | 7669 | 2.36 (1.83–3.04) |
C | 18 | 5380 | 14 | 1222 | 3.53 (1.71–7.29) | 84 | 35296 | 29 | 8289 | 1.42 (0.91–2.21) |
D | 43 | 5367 | 17 | 1220 | 1.45 (0.79–2.64) | 137 | 34694 | 38 | 8162 | 1.14 (0.77–1.68) |
G | 22 | 5375 | 14 | 1221 | 2.38 (1.16–4.88) | 104 | 35374 | 24 | 8408 | 0.97 (0.61–1.54) |
H | 209 | 5286 | 133 | 1157 | 3.07 (2.45–3.85) | 569 | 32328 | 183 | 6925 | 1.65 (1.38–1.97) |
J | 1986 | 4300 | 524 | 941 | 1.27 (1.15–1.41) | 1674 | 13312 | 361 | 2739 | 1.28 (1.10–1.49) |
L | 4 | 5386 | 12 | 1221 | 12.46 (3.94–39.42) | 15 | 35964 | 13 | 8476 | 3.33 (1.52–7.29) |
M | 15 | 5383 | 14 | 1221 | 3.64 (1.66–7.97) | 155 | 35291 | 59 | 8214 | 1.75 (1.27–2.41) |
N | 31 | 5368 | 16 | 1217 | 2.22 (1.20–4.12) | 125 | 35335 | 40 | 8316 | 1.35 (0.93–1.97) |
P | 44 | 5368 | 30 | 1211 | 3.05 (1.88–4.94) | 172 | 34891 | 60 | 8060 | 1.73 (1.27–2.35) |
R | 808 | 4969 | 248 | 1097 | 1.42 (1.23–1.65) | 1251 | 22989 | 312 | 4907 | 1.26 (1.09–1.45) |
S | 43 | 5368 | 25 | 1217 | 2.29 (1.37–3.83) | 104 | 34572 | 26 | 8035 | 1.03 (0.65–1.64) |