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Table 3 De novo type 2 diabetes at follow-up of liver transplant recipients with NASH

From: Risk of de novo post-transplant type 2 diabetes in patients undergoing liver transplant for non-alcoholic steatohepatitis

 

NASH w/o DM

Controls w/o DM

Relative risk (95 % CI)

p

Incidence of de novo DM at:

    

6 months follow-up

499 (19.2 %)

1,737 (13.9 %)

1.38 (1.26–1.51)

<0.0001

1 year follow-up

344 (14.3 %)

1144 (9.8 %)

1.46 (1.31–1.64)

<0.0001

3 years follow-up

186 (11.4 %)

560 (6.8 %)

1.67 (1.43–1.96)

<0.0001

5 years follow-up

73 (7.4 %)

275 (5.2 %)

1.43 (1.12–1.84)

0.0046

Had at least one onset of de novo post-transplant DM by:

    

1 year follow-up

624 (22.9 %)

2,196 (16.7 %)

1.37 (1.27–1.49)

<0.0001

3 years follow-up

578 (32.7 %)

2,004 (22.4 %)

1.46 (1.35–1.57)

<0.0001

5 years follow-up

425 (39.8 %)

1,548 (27.0 %)

1.47 (1.35–1.61)

<0.0001

Recorded resolution of post-transplant DM after the first onset

621 (73.8 %)

2,205 (74.7 %)

0.99 (0.94–1.03)

0.59

Time from onset to resolution, years

1.13 ± 1.06

1.07 ± 0.99

 

0.35

Long-term de novo post-transplant DM

174 (7.6 %)

481 (4.3 %)

1.76 (1.49–2.08)

<0.0001