Comparison of 10-day sequential therapy with 7-day standard triple therapy for Helicobacter pylori eradication in inactive peptic ulcer disease and the efficiency of sequential therapy in inactive peptic ulcer disease and non-ulcer dyspepsia

Table 4 Adverse events in sequential therapy

	Triple	iDU Sequential	NUD Sequential	Total Sequential
Adverse event	(N = 44)	(N = 126)	(N = 238)	(N = 364)
Taste disturbance	6.8 %	7.10 %	7.60 %	7.40 %
Diarrhea	0.0 %	2.40 %	0.40 %	1.10 %
Abdominal discomfort	0.0 %	3.20 %	0.40 %	1.40 %
Skin rash	0.0 %	1.60 %	0.80 %	1.10 %
Nausea	2.3 %	0.00 %	0.80 %	0.50 %
Poor appetite	0.0 %	0.00 %	0.40 %	0.30 %
Dizziness	0.0 %	2.40 %	0.40 %	1.10 %
Mouth bitterness	11.4 %	28.60 %	11.30 %	17.30 %
Loose stool	2.3 %	3.20 %	7.10 %	5.80 %
Cramp	0.0 %	0.80 %	0.00 %	0.30 %
Total	22.7 %	49.20 %	29.40 %	36.30 %
P value (triple vs total sequential)		0.08

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