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Table 2 HER2 expression in gastric cancer: analysing studies with patients from different parts of the world

From: Association between HER2 status in gastric cancer and clinicopathological features: a retrospective study using whole-tissue sections

Study Year Patients’ place of origin Number of patients HER2 positive rate (%) Association with clinicopathological features
Bang YJ [6] 2010 ToGA trial (Multicenter) 3,665 16.6 Topography (GEJ)
Intestinal-type
Begnami MD [19] 2011 Brazil (Single center) 221 8.0 Intestinal-type
Low-grade
Cruz-Reyes C [45] 2013 Mexico (Single center) 269 3.7 Intestinal-type
Cho J [32] 2013 South Korea (Single center) 2,798 7.3 Older age
Male gender
Intestinal-type
Upper-third stomach
Higher lymph node stage
Advanced staging
Shan L [17] 2013 China (Single center) 1,463 9.8 Topography (GEJ)
Intestinal-type
Low-grade
Matsusaka S [35] 2015 Japan (Multicenter) 1,461 15.6 Intestinal-type
Hepatic metastasis
Absence of peritoneal metastasis
Cappellesso R [34] 2015 Europe (Multicenter) 1,040 11.0 Intestinal-type
Low-grade
Laboissiere RS 2015 Brazil (Single Center) 124 10.5 Intestinal-type
Low-grade
Lymphovascular invasion
  1. GEJ gastroesophageal junction