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Table 1 Association between HER2 status and clinicopathological parameters

From: Association between HER2 status in gastric cancer and clinicopathological features: a retrospective study using whole-tissue sections

  Overall HER2 positive HER2 negative P value HER2 (3+) HER2 (2+) HER2 (0, 1+) P value
  n = 124 (%) 13(10.5) 111 (89.5)   13(10.5) 10 (8.1) 101(81.4)  
Age at diagnosis    0.803     0.590
≥60 years 82 (66.1) 9 73   9 8 65  
<60 years 42 (33.9) 4 38   4 2 36  
Gender    0.865     0.459
Male 64 (51.6) 7 57   7 7 50  
Female 60 (48.4) 6 54   6 3 51  
Tumor topography    0.720     0.709
Distal stomach 100(80.6) 10 90   10 9 81  
Proximal stomach/GEJ 24 (19.4) 3 21   3 1 20  
Histological subtype    0.048     0.009
Intestinal 61 (49.2) 11 50   11 9 41  
Diffuse 21 (16.9) 0 21   0 0 21  
Mixed 33 (26.6) 2 31   2 1 30  
Unditermined 9 (7.3) 0 9   0 0 9  
Histological grade    0.004     <0.001
Well 13 (10.5) 4 9   4 1 8  
Moderately 45 (36.3) 7 38   7 8 30  
Poorly 66 (53.2) 2 64   2 1 63  
Lymphovascular invasion    0.031     0.060
Positive 94 (75.8) 13 81   13 6 75  
Negative 30 (24.2) 0 30   0 4 26  
Blood-vessel invasion    0.395     0.170
Positive 44 (35.5) 6 38   6 1 37  
Negative 80 (64.5) 7 73   7 9 64  
pT status    0.271     0.165
pT1 17 (13.7) 0 17   0 1 16  
pT2 32 (25.8) 3 29   3 2 27  
pT3 69 (55.6) 10 59   10 5 54  
pT4 6 (4.9) 0 6   0 2 4  
pN status    0.453     0.762
pN0 39 (31.5) 2 37   2 4 33  
pN1 46 (37.1) 7 39   7 4 35  
pN2 24 (19.3) 3 21   3 1 20  
pN3 15 (12.1) 1 14   1 1 13  
pM status    0.548     0.705
pM0 121(97.6) 13 108   13 10 98  
pM1 3 (2.4) 0 3   0 0 3  
  1. Bold numbers represent P values with statistical significance