|
Select genes involved in IL-6 signaling
|
|
IL-6
|
not on RNA-seq readout
|
|
IL-6R
|
29.55
|
30.89
|
1.05
|
0.80
|
|
gp130
|
26.04
|
23.44
|
−1.11
|
0.44
|
|
Jak1
|
34.9
|
34.1
|
−1.02
|
0.66
|
|
Jak2
|
1.87
|
1.81
|
−1.03
|
0.78
|
|
Jak3
|
2.02
|
2.78
|
1.37
|
0.034
|
|
Stat3
|
15.43
|
16.20
|
1.05
|
0.68
|
|
Socs3
|
2.49
|
3.44
|
1.38
|
0.47
|
|
Select genes involved in TNF-α signaling
|
|
TNF-α
|
0.02
|
0.03
|
1.56
|
0.38
|
|
Tnfrsf1b
|
3.91
|
2.88
|
−1.36
|
0.08
|
|
Traf2
|
6.96
|
7.06
|
1.01
|
0.81
|
|
Rela (p65)
|
10.56
|
10.64
|
1.01
|
0.89
|
|
Nfkbia (IkBa)
|
18.57
|
18.35
|
−1.01
|
0.90
|
|
Select genes involved in IL-1β signaling
|
|
IL-1β
|
1.99
|
2.93
|
1.47
|
0.013
|
|
IL-1R1
|
6.38
|
6.79
|
1.07
|
0.75
|
|
Traf6
|
1.45
|
1.30
|
−1.12
|
0.23
|
|
Mapk8 (JNK1)
|
2.24
|
1.98
|
−1.13
|
0.32
|
|
Mapk9 (JNK2)
|
18.27
|
19.25
|
1.05
|
0.52
|
|
Select genes encoding acute phase response proteins
|
|
Apcs
|
1048
|
862
|
−1.22
|
0.047
|
|
Apoh
|
3874
|
3401
|
−1.07
|
0.006
|
|
C2
|
51.0
|
47.0
|
−1.09
|
0.10
|
|
C9
|
517
|
614
|
1.19
|
0.10
|
|
Crp
|
not on RNA-seq readout
|
|
F2
|
1051
|
1060
|
1.01
|
0.86
|
|
Fth1
|
1817
|
1969
|
1.08
|
0.18
|
|
Hmox1
|
16.3
|
17.0
|
1.05
|
0.62
|
|
Hp
|
1299
|
1603
|
1.24
|
0.0002
|
|
Hpx
|
2667
|
3086
|
1.16
|
0.11
|
|
IL-1rn
|
13.7
|
11.5
|
−1.19
|
0.35
|
|
Lbp
|
538
|
350
|
−1.54
|
0.002
|
|
Mur2
|
432
|
392
|
−1.10
|
0.31
|
|
Pf4
|
2.48
|
5.04
|
2.03
|
0.0004
|
|
Plg
|
944
|
868
|
−1.08
|
0.11
|
|
Sod2
|
41.8
|
47.2
|
1.13
|
0.013
|
|
Select genes representative of macrophage markers
|
|
Cd68
|
12.69
|
12.94
|
1.02
|
0.86
|
|
Emr1 (F4/80)
|
4.33
|
4.89
|
1.13
|
0.32
|
|
Itgax (Cd11c)
|
0.27
|
0.42
|
1.53
|
0.044
|
|
Itgam (Cd11b)
|
0.37
|
0.37
|
−1.01
|
0.92
|
