Table 1 Associations of HDAC-1 and −2 expression with clinicopathological parameters in 70 pancreatic adenocarcinoma patients
Clinicopathological characteristics | HDAC-1 expression | HDAC-2 expression | ||||
|---|---|---|---|---|---|---|
Low (%) | High (%) | p-value | Low (%) | High (%) | p-value | |
N = 70 | 42 (60.0) | 28 (40.0) | 35 (50.0) | 35 (50.0) | ||
Age (mean ± SD;ys) | 0.4880 | 0.8082 | ||||
≤66.77 ± 8.94 yrs | 16 (22.9) | 13 (18.6) | 14 (20.0) | 15 (21.4) | ||
>66.77 ± 8.94 yrs | 26 (37.1) | 15 (21.4) | 21 (30.0) | 20 (28.6) | ||
Gender | 0.4191 | 0.6207 | ||||
Male | 28 (40.0) | 16 (22.9) | 23 (32.9) | 21 (30.0) | ||
Female | 14 (20.0) | 12 (17.1) | 12 (17.1) | 14 (20.0) | ||
Histopathological grade | 1.0000 | 0.4945 | ||||
I + II | 36 (51.4) | 24 (34.3) | 29 (41.4) | 31 (44.3) | ||
I II | 6 (8.6) | 4 (5.7) | 6 (8.6) | 4 (5.7) | ||
pT | 0.1544 | 0.2046 | ||||
T1 + T2 | 5 (7.1) | 7 (10.0) | 4 (5.7) | 8 (11.4) | ||
T3 + T4 | 37 (52.9) | 21 (30.0) | 31 (44.3) | 27 (38.6) | ||
pN | 0.0632 | 0.2312 | ||||
0 | 16 (22.9) | 17 (24.3) | 19 (27.1) | 14 (20.0) | ||
1 | 26 (37.1) | 11 (15.7) | 16 (22.9) | 21 (30.0) | ||
pM | 0.5282 | 1.0000 | ||||
0 | 39 (55.7) | 27 (38.6) | 33 (47.1) | 33 (47.1) | ||
1 | 3 (4.3) | 1 (1.4) | 2 (2.9) | 2 (2.9) | ||
pStage | 0.1127 | 0.2320 | ||||
I + II | 31 (44.3) | 25 (35.7) | 26 (37.1) | 30 (42.9) | ||
III + IV | 11 (15.7) | 3 (4.3) | 9 (12.9) | 5 (7.1) | ||
Ki-protein statement | 0.0238 | 0.4703 | ||||
≤ median value | 28 (40.0) | 11 (15.7) | 21 (30.0) | 18 (15.7) | ||
> median value | 14 (20.0) | 17 (24.3) | 14 (20.0) | 17 (24.3) | ||