Member of commercial health insurance plan, with medical coverage and pharmacy benefits, and presence of qualifying eventa during the accrual period
| |
156,682 (100.0 %)
| |
231,793 (100 %)
| |
1,314,147 (100 %)
| |
1,577,784 (100 %)
|
Baseline exclusions
| | | | | | | | |
Less than 18 years at index date
|
1396
|
155,286 (99.1 %)
|
2482
|
229,311 (98.9 %)
|
33,476
|
1,280,671 (97.5 %)
|
60,552
|
1,517,232 (96.2 %)
|
Less than 12 months prior continuous enrollment
|
79,819
|
75,467 (48.2 %)
|
136,147
|
93,164 (40.2 %)
|
780,943
|
499,728 (38.0 %)
|
791,027
|
726,205 (46.0 %)
|
Prior dispensing of study drug or drug class in the baseline
|
0
|
75,467 (48.2 %)
|
23,753
|
69,411 (29.9 %)
|
134,294
|
365,434 (27.8 %)
|
334,496
|
391,709 (24.8 %)
|
Had no depression diagnosis in the baseline
|
27,596
|
47,871 (30.6 %)
|
24,844
|
44,567 (19.2 %)
|
153,173
|
212,261 (16.2 %)
|
0
|
391,709 (24.8 %)
|
Had hepatic injury/chronic hepatic condition in the baseline
|
10,592
|
37,279 (23.8 %)
|
9173
|
35,394 (15.3 %)
|
39,354
|
172,907 (13.2 %)
|
76,815
|
314,894 (20.0 %)
|
Region affected by Hurricane Katrina
|
489
|
36,790 (23.5 %)
|
509
|
34,885 (15.1 %)
|
2020
|
170,887 (13.0 %)
|
3556
|
311,338 (19.7 %)
|
Cohort assignment based on earliest qualifying index date (pre-propensity score matching)
|
30,844 (19.7 %)
|
29,243 (12.6 %)
|
166,236 (12.6 %)
|
311,338 (19.7 %)
|