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Fig. 3 | BMC Gastroenterology

Fig. 3

From: Decreased PCSK9 expression in human hepatocellular carcinoma

Fig. 3

Comparison of LDL-receptor immunohistochemical staining in hepatocellular carcinoma and adjacent liver tissue (a) Total intensity of positives of 184722732 ± 15287852.05 pixel intensity versus 91021737 ± 8108288.90 pixel intensity (p-value < 0.0001); (b) Total intensity of strong positives of 4329282 ± 887724.04 versus 1066570 ± 235470.9 pixel intensity (p-value < 0.0001); (c) Positivity of 0.992 ± 0.001 versus 0.986 ± 0.002 (p-value = 0.013); (d) Proportion of strong positives of 0.022 ± 0.004 versus 0.009 ± 0.002 (p-value < 0.0001). (e) Representative core of hepatocellular carcinoma, strongly staining with LDL-R antibody; (f) Representative core of cirrhosis staining with LDL-R antibody

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