Fig. 1

Comparison of PCSK9 immunohistochemical staining in hepatocellular carcinoma and adjacent liver tissue. a Total intensity of positives of 30413022.89 ± 2916711.84 pixel intensity versus 47844692.78 ± 3501425.25 pixel intensity (p-value < 0.0001); (b) Total intensity of strong positives of 244849.22 ± 30352.09 versus 591716 ± 95497.21 pixel intensity (p-value < 0.0001); (c) Positivity of 0.72 ± 0.03 versus 0.89 ± 0.009 (p-value < 0.0001); (d) proportion of strong positives of 0.005 ± 0.0003 versus 0.011 ± 0.001 (p-value < 0.0001); (e) Representative core of hepatocellular carcinoma adjacent to cirrhosis, stained with PCSK9 antibody; (f) Representative core of cirrhosis strongly staining with PCSK9 antibody