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Table 4 Predictors of early recurrence after LT for HCC

From: Excessive intraoperative blood loss independently predicts recurrence of hepatocellular carcinoma after liver transplantation

Variable

Univariate analysis

Multivariate analysis

P

HR (95 % CI) P

Age <60 years

0.022

1.27 (0.87–1.86) 0.217

Male sex

0.080

 

Hepatitis B virus infection

0.712

 

Pre-LT tumor therapy

0.203

 

AFP levels > 400 ng/mL

<0.001

1.71 (1.24–2.78) 0.001

Poor differentiation

0.020

1.31 (0.84–2.03) 0.232

Macrovascular invasion

<0.001

3.26 (2.29–4.64) <0.001

Microvascular invasion

<0.001

1.94 (1.40–2.71) <0.001

Beyond Milan criteria

<0.001

2.12 (1.41–3.20) <0.001

Blood transfusion

0.077

 

IBL > 4 L

<0.001

2.45 (1.64–3.66) <0.001