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Table 3 Association between histologic and symptomatic presentation and growth disturbance

From: Factors associated with growth disturbance at celiac disease diagnosis in children: A retrospective cohort study

  n a Growth failure, % Odds ratio 95 % CI P value
Degree of small-bowel mucosal villous atrophy
 Partial 174 20.7 1   
 Subtotal 194 34.5 2.02 1.26 - 3.24 0.003
 Total 126 52.4 4.22 2.54 - 7.00 <0.001
Severity of symptomsb
 Mild 258 28.7 1   
 Moderate 107 35.5 1.37 0.85 - 2.21 0.198
 Severe 43 58.1 3.45 1.78 - 6.70 <0.001
Asymptomatic 121 37.2 1.47 0.93 - 2.33 0.097
 Diarrhea
 No 319 32.3 1   
 Yes 181 37.6 1.26 0.86 - 1.85 0.232
Abdominal pain
 No 267 42.7 1   
 Yes 230 25.7 0.46 0.32 - 0.68 <0.001
Constipation
 No 425 35.8 1   
 Yes 72 26.4 0.64 0.37 - 1.13 0.124
Vomiting
 No 466 32.4 1   
 Yes 32 59.4 3.05 1.47 - 6.34 0.003
Anemia      
 No 420 32.4 1   
 Yes 91 37.4 1.25 0.78 - 2.00 0.361
  1. aData available
  2. bGrowth failure was not considered as a symptom here at diagnosis in 530 children with celiac disease