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Table 3 Association between histologic and symptomatic presentation and growth disturbance

From: Factors associated with growth disturbance at celiac disease diagnosis in children: A retrospective cohort study

 

n a

Growth failure, %

Odds ratio

95 % CI

P value

Degree of small-bowel mucosal villous atrophy

 Partial

174

20.7

1

  

 Subtotal

194

34.5

2.02

1.26 - 3.24

0.003

 Total

126

52.4

4.22

2.54 - 7.00

<0.001

Severity of symptomsb

 Mild

258

28.7

1

  

 Moderate

107

35.5

1.37

0.85 - 2.21

0.198

 Severe

43

58.1

3.45

1.78 - 6.70

<0.001

Asymptomatic

121

37.2

1.47

0.93 - 2.33

0.097

 Diarrhea

 No

319

32.3

1

  

 Yes

181

37.6

1.26

0.86 - 1.85

0.232

Abdominal pain

 No

267

42.7

1

  

 Yes

230

25.7

0.46

0.32 - 0.68

<0.001

Constipation

 No

425

35.8

1

  

 Yes

72

26.4

0.64

0.37 - 1.13

0.124

Vomiting

 No

466

32.4

1

  

 Yes

32

59.4

3.05

1.47 - 6.34

0.003

Anemia

     

 No

420

32.4

1

  

 Yes

91

37.4

1.25

0.78 - 2.00

0.361

  1. aData available
  2. bGrowth failure was not considered as a symptom here at diagnosis in 530 children with celiac disease