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Table 1 Baseline characteristics in 530 children with or without growth failure before celiac disease diagnosis

From: Factors associated with growth disturbance at celiac disease diagnosis in children: A retrospective cohort study

  

Growth failure n = 182

 

Normal growth n = 348

 
 

n a

Median (Q1, Q3)

n a

Median (Q1, Q3)

P value

Age at diagnosis, yr

182

6.3 (2.5, 11.7)

348

8.0 (5.0, 12.0)

<0.001

Age of menarche, yr

23

13.0 (12.0, 13.0)

45

12.0 (12.0, 13.0)

0.146

Height, SDb

45

−0.5 (−1.2, 0.4)

134

0.2 (−0.5, 0.9)

0.004

Weight, SD

34

−1.1 (−1.9, −0.2)

114

−0.3 (−0.9, 0.6)

0.003

Weight/height percentage

65

−9.0 (−15.0, −1.0)

163

0.1 (−8.0, 9.0)

<0.001

Body mass index, kg/m2

68

15.7 (14.3, 16.6)

155

16.6 (15.1, 19.2)

<0.001

EmA, titer

81

500 (200, 2000)

205

200 (100, 1000)

<0.001

TG2ab, U/lc

98

120.0 (71.3, 120.0)

253

120.0 (39.0, 120.0)

0.035

Hemoglobin, g/l

129

122 (115, 128)

248

126 (115, 133)

0.016

MCV, fl

96

81 (75, 83)

207

81 (76, 83)

0.662

Alkaline phosphatase, U/l

42

309 (148, 511)

79

231 (184, 322)

0.180

ALT, U/l

34

24 (18, 32)

83

20 (16, 25)

0.035

Total iron, μmol/l

33

10.0 (6.6, 15.0)

58

12.5 (9.3, 17.8)

0.304

Albumin, g/l

18

37 (34, 41)

50

39 (37, 41)

0.252

TSH, mU/l

43

2.8 (2.2, 3.7)

58

2.4 (1.6, 3.1)

0.013

Thyroxin, pmol/l

31

14.4 (12.6, 16.9)

25

14.8 (12.9, 16.3)

0.817

  1. Q1, Q3, lower and upper quartiles; SD, standard deviation; EmA, endomysial antibodies; TG2ab, transglutaminase 2 antibodies; MCV, mean corpuscular volume; ALT, alanine aminotransferase; TSH, thyroid stimulating hormone
  2. aData available
  3. bIncludes only measurements made by a pediatrician at the time of gastrointestinal endoscopy
  4. cUpper limit of the assay 120.0 U/l