| |
Growth failure n = 182
| |
Normal growth n = 348
| |
---|
|
n
a
|
Median (Q1, Q3)
|
n
a
|
Median (Q1, Q3)
|
P value
|
---|
Age at diagnosis, yr
|
182
|
6.3 (2.5, 11.7)
|
348
|
8.0 (5.0, 12.0)
|
<0.001
|
Age of menarche, yr
|
23
|
13.0 (12.0, 13.0)
|
45
|
12.0 (12.0, 13.0)
|
0.146
|
Height, SDb
|
45
|
−0.5 (−1.2, 0.4)
|
134
|
0.2 (−0.5, 0.9)
|
0.004
|
Weight, SD
|
34
|
−1.1 (−1.9, −0.2)
|
114
|
−0.3 (−0.9, 0.6)
|
0.003
|
Weight/height percentage
|
65
|
−9.0 (−15.0, −1.0)
|
163
|
0.1 (−8.0, 9.0)
|
<0.001
|
Body mass index, kg/m2
|
68
|
15.7 (14.3, 16.6)
|
155
|
16.6 (15.1, 19.2)
|
<0.001
|
EmA, titer
|
81
|
500 (200, 2000)
|
205
|
200 (100, 1000)
|
<0.001
|
TG2ab, U/lc
|
98
|
120.0 (71.3, 120.0)
|
253
|
120.0 (39.0, 120.0)
|
0.035
|
Hemoglobin, g/l
|
129
|
122 (115, 128)
|
248
|
126 (115, 133)
|
0.016
|
MCV, fl
|
96
|
81 (75, 83)
|
207
|
81 (76, 83)
|
0.662
|
Alkaline phosphatase, U/l
|
42
|
309 (148, 511)
|
79
|
231 (184, 322)
|
0.180
|
ALT, U/l
|
34
|
24 (18, 32)
|
83
|
20 (16, 25)
|
0.035
|
Total iron, μmol/l
|
33
|
10.0 (6.6, 15.0)
|
58
|
12.5 (9.3, 17.8)
|
0.304
|
Albumin, g/l
|
18
|
37 (34, 41)
|
50
|
39 (37, 41)
|
0.252
|
TSH, mU/l
|
43
|
2.8 (2.2, 3.7)
|
58
|
2.4 (1.6, 3.1)
|
0.013
|
Thyroxin, pmol/l
|
31
|
14.4 (12.6, 16.9)
|
25
|
14.8 (12.9, 16.3)
|
0.817
|
- Q1, Q3, lower and upper quartiles; SD, standard deviation; EmA, endomysial antibodies; TG2ab, transglutaminase 2 antibodies; MCV, mean corpuscular volume; ALT, alanine aminotransferase; TSH, thyroid stimulating hormone
- aData available
- bIncludes only measurements made by a pediatrician at the time of gastrointestinal endoscopy
- cUpper limit of the assay 120.0 U/l