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Table 1 Baseline characteristics in 530 children with or without growth failure before celiac disease diagnosis

From: Factors associated with growth disturbance at celiac disease diagnosis in children: A retrospective cohort study

   Growth failure n = 182   Normal growth n = 348  
  n a Median (Q1, Q3) n a Median (Q1, Q3) P value
Age at diagnosis, yr 182 6.3 (2.5, 11.7) 348 8.0 (5.0, 12.0) <0.001
Age of menarche, yr 23 13.0 (12.0, 13.0) 45 12.0 (12.0, 13.0) 0.146
Height, SDb 45 −0.5 (−1.2, 0.4) 134 0.2 (−0.5, 0.9) 0.004
Weight, SD 34 −1.1 (−1.9, −0.2) 114 −0.3 (−0.9, 0.6) 0.003
Weight/height percentage 65 −9.0 (−15.0, −1.0) 163 0.1 (−8.0, 9.0) <0.001
Body mass index, kg/m2 68 15.7 (14.3, 16.6) 155 16.6 (15.1, 19.2) <0.001
EmA, titer 81 500 (200, 2000) 205 200 (100, 1000) <0.001
TG2ab, U/lc 98 120.0 (71.3, 120.0) 253 120.0 (39.0, 120.0) 0.035
Hemoglobin, g/l 129 122 (115, 128) 248 126 (115, 133) 0.016
MCV, fl 96 81 (75, 83) 207 81 (76, 83) 0.662
Alkaline phosphatase, U/l 42 309 (148, 511) 79 231 (184, 322) 0.180
ALT, U/l 34 24 (18, 32) 83 20 (16, 25) 0.035
Total iron, μmol/l 33 10.0 (6.6, 15.0) 58 12.5 (9.3, 17.8) 0.304
Albumin, g/l 18 37 (34, 41) 50 39 (37, 41) 0.252
TSH, mU/l 43 2.8 (2.2, 3.7) 58 2.4 (1.6, 3.1) 0.013
Thyroxin, pmol/l 31 14.4 (12.6, 16.9) 25 14.8 (12.9, 16.3) 0.817
  1. Q1, Q3, lower and upper quartiles; SD, standard deviation; EmA, endomysial antibodies; TG2ab, transglutaminase 2 antibodies; MCV, mean corpuscular volume; ALT, alanine aminotransferase; TSH, thyroid stimulating hormone
  2. aData available
  3. bIncludes only measurements made by a pediatrician at the time of gastrointestinal endoscopy
  4. cUpper limit of the assay 120.0 U/l