Study | Design and methods | Level of evidencea | Definition of constipation | Definition of successful treatment |
---|---|---|---|---|
Chan [13] | Prospective cohort study | III | Infrequent passage of stool +/− straining/ digitation/ incomplete emptying | i) → Improvement in Cleveland Constipation Score |
ii) → Patient-reported satisfaction | ||||
Christensen [9] | Retrospective questionnaire survey and case note review | III | Idiopathic constipation including slow transit, obstructed defecation and ‘undetermined’ | i) → Ongoing use |
ii) → Resolved symptoms | ||||
iii) → Still using irrigation at time of death | ||||
Koch [14] | Prospective cohort study | III | <2 bowel motions per week, straining or incomplete evacuation >50 % motions in previous year | Resolution of incomplete emptying or straining symptoms |
Cazemier [15] | Retrospective case series questionnaire survey | III | Constipation according to Rome II criteria | Patient-reported satisfaction |
Gosselink [16] | Retrospective case series, questionnaire survey | III | Obstructed defecation based on; straining, incomplete evacuation, digitation, fullness, <3 motions/ week | Patient-reported satisfaction |
Gardiner [18] | Case series; not stated if prospective or retrospective | III | Obstructive defecation and slow transit (?which criteria used) | Patient-reported satisfaction |
Crawshaw [17] | Retrospective case note review and questionnaire survey | III | The inability to evacuate the rectum when desired (includes obstructed defecation and dyssynergic defecation) | 10 mm increase on VAS (10 % improvement) |