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Table 1 Characteristics of the study population

From: Validation of coding algorithms for the identification of patients hospitalized for alcoholic hepatitis using administrative data

  Entire cohort (n = 228) Confirmed AH cases (n = 122) Unconfirmed AH cases (n = 106) P-value
Age, years 49 (43–55) 49 (42–55) 49 (44–58) 0.33
Male 61 % (138) 60 % (73) 61 % (65) 0.89
Self-reported alcohol consumption, g/day 119 (81–224) 121 (84–233) 112 (56–208) 0.024
Excessive intake a 91 % (208) 100 % (122) 81 % (86) <0.001
Proportion in the highest intake quartile 25 % (50) 25 % (29) 24 % (21) 0.87
Admission hospital     0.69
1 39 % (90) 42 % (51) 37 % (39)
2 30 % (68) 29 % (36) 31 % (32)
3 31 % (70) 29 % (35) 33 % (35)
Year of admission     0.16
2008 25 % (56) 22 % (27) 27 % (29)
2009 17 % (40) 15 % (18) 21 % (22)
2010 18 % (41) 17 % (21) 19 % (20)
2011 21 % (48) 21 % (26) 21 % (22)
2012 19 % (43) 25 % (30) 12 % (13)
Biochemical status     
Maddrey DF 29 (13–52) 45 (26–62) 12 (5–30) <0.001
MELD 18 (13–23) 21 (18–24) 13 (8–19) <0.001
Severe b 62 % (142) 80 % (97) 42 % (45) <0.001
Associated conditions     
Cirrhosis 25 % (58) 29 % (35) 22 % (23) 0.29
Ascites 27 % (61) 38 % (46) 14 % (15) <0.001
GI hemorrhage 34 % (77) 39 % (48) 27 % (29) 0.07
Hepatic encephalopathy 2.6 % (6) 2.5 % (3) 2.8 % (3) 1
Malnutrition 3.0 % (7) 4.1 % (5) 1.9 % (2) 0.45
HRS/renal failure 16 % (36) 18 % (22) 13 %(14) 0.37
Pancreatitis 7.9 % (18) 4.9 % (6) 11 % (12) 0.09
Alcohol abuse 36 % (81) 38 % (46) 33 % (35) 0.49
Alcohol dependence 26 % (60) 28 % (34) 25 % (26) 0.65
Alcohol withdrawal 21 % (47) 16 % (19) 26 % (28) 0.05
Mortality     
In-hospital 5.7 % (13) 7.4 % (9) 3.7 % (4) 0.27
90 days 13 % (29) 17 % (21) 8.5 % (9) 0.045
180 day 17 % (38) 23 % (28) 11 % (12) 0.007
  1. Data are presented as median (IQR) or % (n). DF discriminant function, GI gastrointestinal, HRS hepatorenal syndrome; MELD, Model for End-Stage Liver Disease
  2. a As defined in the Methods
  3. b Severe presentation is characterized by a Maddrey DF of ≥32 and/or the presence of hepatic encephalopathy