Table 2 Assessment of gastroesophageal reflux with and without administration of acotiamide
From: Effects of acotiamide on esophageal motor function and gastroesophageal reflux in healthy volunteers
| 24 h | Post prandial (6 h) | |||||
|---|---|---|---|---|---|---|
| Control | Acotiamide | p value | Control | Acotiamide | p value | |
| pH <4 (%) | 1.1 [0.5–2.0] | 0.6 [0.3–2.4] | 0.47 | 2.0 [0.3–3.3] | 2.0 [0.8–2.6] | 0.99 |
| Number of reflux episodes | ||||||
| Total reflux | 56.0 [44.0–76.5] | 56.0 [25.0–81.5] | 0.96 | 34.0 [23.5–40.5] | 34.0 [18.0–48.5] | 0.58 |
| Acid reflux | 31.0 [23.0–43.5] | 25.0 [15.5–46.0] | 0.76 | 17.0 [8.5–24.5] | 15.0 [10.5–26.0] | 0.45 |
| Bolus clearance time (s) | 14.0 [12.0–15.0] | 14.0 [13.0–18.5] | 0.11 | 14.0 [12.5–17.5] | 16.0 [14.5–19.0] | 0.17 |
