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Table 1 Factors associated with overall survival in operated patients with PDAC

From: Fibroblast activation protein-α-expressing fibroblasts promote the progression of pancreatic ductal adenocarcinoma

  Univariate analysis Multivariate analysis
Factor Hazard ratio 95 % CI P value Hazard ratio 95 % CI P value
Age (≥65)    0.631    
Gender    0.384    
Smoking    0.206    
Alcohol 2.082 1.103-3.930 0.024 1.941 1.024-3.678 0.042
DM    0.966    
Chemotherapya    0.219    
Tumor factor       
  T3 or T4b    0.513    
  N1b    0.115    
  M1b 2.863 1.072-7.646 0.036 2.972 1.097-8.055 0.032
Stage III or IVc    0.271    
Histological factor       
  ly1    0.659    
  v2    0.195    
  n3    0.270    
FAP moderate/strong 2.540 1.273-5.068 0.008 2.534 1.267-5.068 0.009
  1. apostoperative, bTNM classification of Union for International Cancer Control (UICC), cclinical stage of PDAC by UICC, 1lymph duct invasion, 2vascular invasion, 3nerve invasion