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Table 1 Factors associated with overall survival in operated patients with PDAC

From: Fibroblast activation protein-α-expressing fibroblasts promote the progression of pancreatic ductal adenocarcinoma

 

Univariate analysis

Multivariate analysis

Factor

Hazard ratio

95 % CI

P value

Hazard ratio

95 % CI

P value

Age (≥65)

  

0.631

   

Gender

  

0.384

   

Smoking

  

0.206

   

Alcohol

2.082

1.103-3.930

0.024

1.941

1.024-3.678

0.042

DM

  

0.966

   

Chemotherapya

  

0.219

   

Tumor factor

      

  T3 or T4b

  

0.513

   

  N1b

  

0.115

   

  M1b

2.863

1.072-7.646

0.036

2.972

1.097-8.055

0.032

Stage III or IVc

  

0.271

   

Histological factor

      

  ly1

  

0.659

   

  v2

  

0.195

   

  n3

  

0.270

   

FAP moderate/strong

2.540

1.273-5.068

0.008

2.534

1.267-5.068

0.009

  1. apostoperative, bTNM classification of Union for International Cancer Control (UICC), cclinical stage of PDAC by UICC, 1lymph duct invasion, 2vascular invasion, 3nerve invasion