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Table 2 Obstetrics and neonatal outcome. Values are given as numbers (%) or mean [SD]

From: Intrahepatic cholestasis of pregnancy: observational study of the treatment with low-dose ursodeoxycholic acid

Characteristic

All (n = 307)

UDCA (n = 208)

No medication (n = 99)

P

Time of delivery (weeks)

37.9 [1.6]

37.4 [1.5]

38.9 [1.2]

p < 0.05

Preterm delivery (<37 weeks)

57 (19 %)

53 (25 %)

4 (4 %)

p < 0.05

Gemini

14 (5 %)

13 (6 %)

1 (1 %)

p > 0.05

Induction of the labour

222 (72 %)

143 (69 %)

79 (80 %)

p < 0.05

Normal vaginal delivery

245 (80 %)

161 (77 %)

84 (85 %)

NS

Children

(n = 321)

(n = 221)

(n = 100)

 

Female

144 (45 %)

98 (44 %)

46 (46 %)

NS

Male

177 (55 %)

123 (56 %)

54 (54 %)

NS

Weight

3344 [531]

3262 [553]

3525 [428]

p < 0.005

Apgar score (5 min)

8.8 [1.0]

8.7 [1.0]

9.0 [0.9]

p < 0.05

Fetal Artery pH

7.28 [0.09]

7.28 [0.09]

7.28 [0.10]

NS

Fetal Artery pH < 7.05

2 (1 %)

2 (1 %)

-

NS

Fetal venous BE, mmol/l

−4.1 [3.2]

−4.0 [3.2]

−4.3 [3.2]

NS

Fetal BE < −12 mmol/l

4 (1 %)

3 (1 %)

1 (1 %)

NS