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Table 1 Patients’ characteristics comparing ursodeoxycholic acid treatment and no medical treatment in ICP. Values are given as numbers (%) or mean [SD]

From: Intrahepatic cholestasis of pregnancy: observational study of the treatment with low-dose ursodeoxycholic acid

  ALL n = 307 No medication n = 99 UDCA n = 208 P
Maternal age (years) 29.6 [5.2] 28.8 [4.6] 29.9 [5.4] NS
Smoking 26 (8 %) 12 (12 %) 14 (7 %) NS
Body mass index 23.5 [4.1] 22.9 [3.7] 23.8 [4.2] NS
Former deliveries (range) 1.0 (0–8) 1.0 (0–8) 0.8 (0–5) NS
ICP in earlier pregnancy 92 (30 %) 27 (27 %) 65 (31 %) NS
Heredity 7 (2 %) 3 (3 %) 4 (2 %) NS
Beginning of itching (wks) 33.6 [3.9] 36.8 [2.5] 32.2 [3.6] P < 0.05
ICP diagnosed (wks) 34.8 [3.5] 38.0 [1.5] 33.3 [3.1] P < 0.05
Bile acid at diagnosis (μmol/l) 19.2 [24.9] 16.7 [26.7] 20.5 [24.0] NS
ALT at diagnosis (U/l) 152.8 [166.1] 96.4 [106.6] 179.2 [181.9] P < 0.05
Abdominal ultrasound 35 (11 %) 4 (4 %) 31 (15 %) p < 0.05
Bile stones 9 (3 %) 1 (1 %) 8 (4 %) NS