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Fig. 6 | BMC Gastroenterology

Fig. 6

From: IGF-1 decreases portal vein endotoxin via regulating intestinal tight junctions and plays a role in attenuating portal hypertension of cirrhotic rats

Fig. 6

a and b Bax was increased and Bcl-2 was decreased in intestines during the development of liver cirrhosis in rats, and administration of IGF-1 attenuated Bax and Bcl-2 changes in intestines of liver cirrhosis rats. c and d Administration of LPS to Caco-2 cells decreased Bax level and increased Bcl-2 level, and IGF-1 attenuated the effect of LPS on Bax and Bcl-2 expressions in Caco-2 cells. Data were shown with the mean ± SD. **P <0.001 vs. control group, ## P <0.001 vs. CCL4 group or LPS group

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BMC Gastroenterology

ISSN: 1471-230X

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