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Table 2 Serum levels of alpha-fetoprotein (AFP) in cirrhotic patients with and without HCC, and the relation to clinical features (Child-Pugh class and BCLC stage)

From: Plasma osteopontin is a biomarker for the severity of alcoholic liver cirrhosis, not for hepatocellular carcinoma screening

AFP (ng/mL)

Group I

Group II

p-value

(Cirrhosis)

(Cirrhosis and HCC)

 

3.00 (0.90-17.00)

11.00 (1.30-431272.00)

<0.001*

Child-Pugh class

  

0.627 **

A

2.50 (1.10-13.00)

10.00 (1.30-2159.00)

B

3.40 (1.10-5.60)

14.00 (1.60-431272.00)

C

3.10 (0.90-17.00)

12.45 (1.40-8251.00)

BCLC Stage a

  

0.007 **

0

 

6.15 (5.90-6.40)

A

 

3.20 (1.30-242.00)

B

 

31.00 (2.80-431272.00)

C

 

225.00 (8.70-7392.00)

D

 

255.00 (3.30-8251.00)

  1. *p - Value by Mann–Whitney U test for comparison of serum AFP between two groups
  2. **p - Value by Kruskal-Wallis test for comparison of serum AFP across Child-Pugh classes and BCLC stages
  3. aBarcelona Clinic Liver Cancer