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Table 3 Biopsy site and proportion of subjects with E. coli-laden macrophages

From: Lamina propria macrophage phenotypes in relation to Escherichia coli in Crohn’s disease

Subject group

CD

UC

Healthy controls

Subject numbers

35

9

18

Biopsy site

   

rectum

11

9

18

colon (other)

9

-

-

ileum

14

-

-

jejunum

1

-

-

Total

25/35 (71 %) (71 %)((71 %)

1/9 (11 %)

0/18 (0 %)

According to histological severity

  

normal

3/7

0/0

0/18

mild

20/26

0/8

-

moderate

2/2

1/1

-

severe

0

0/0

-

According to endoscopic severity score

  

CD patients

  

SES-CD (biopsied segment)

  

0

0/3

  

1-2

-

  

3

6/11

  

4

13/15

  

5-7

6/6

  

>7

-

  

SES-CD (total score)

   

0

0/3

  

1-2

-

  

3-4

8/14

  

5-8

9/10

  

9-13

7/7

  

>13

-

  

UC patients

   

Modified Baron score

  

0

 

-

 

1

 

0/8

 

2

 

1/1

 

3

 

-

 
  1. patient with jejunal CD - SES-CD total not recorded as no colonoscopy
  2. HC healthy controls; UC ulcerative colitis; CD Crohn’s disease