Relation of cholesterol metabolism to pediatric gallstone disease: a retrospective controlled study

BMC Gastroenterology

Table 4 Comparison of serum cholesterol, squalene and non-cholesterol sterols in patients with gallstones and controls

	BPS	CS	Controls	P
	(n = 17)	(n = 11)	(n = 82)
Cholesterol	129 ± 9^a	158 ± 9	145 ± 3	0.042
Squalene¹	23 ± 2^b	28 ± 3^c	17 ± 1	0.003
Lanosterol¹	8 ± 2	11 ± 1	−²	0.167
Cholestenol¹	31 ± 4^d	24 ± 5^e	15 ± 2	0.010
Lathosterol¹	137 ± 17^f	168 ± 21^g	87 ± 8	0.007
Desmosterol¹	107 ± 7^h	104 ± 8	86 ± 3	0.035
Cholestanol¹	186 ± 9ⁱ	126 ± 11^j	168 ± 4	<0.001
Campesterol1	312 ± 34^k	207 ± 41^l	310 ± 15	<0.001
Sitosterol¹	170 ± 18^m	117 ± 22ⁿ	176 ± 8	0.001
Avenasterol¹	45 ± 4	40 ± 5^o	48 ± 2	0.037
Stigmasterol¹	17 ± 3^p	17 ± 3^q	29 ± 1	<0.001
Lathosterol/Campesterol	0.58 ± 0.19^r	1.87 ± 0.68^s	0.34 ± 0.02	<0.001

Values are mean ± SEM
BPS black pigment stones, CS cholesterol stones
¹100× mmol/mol of cholesterol
²Not determined
^aP = 0.045 compared to CS. ^bP = 0.015 and ^cP < 0.001 compared to controls. ^dP =0.002 and ^eP = 0.009 compared to controls. ^fP = 0.006 and ^gP = 0.029 compared to controls. ^hP = 0.003 compared to controls. ⁱP < 0.001 compared to CS and P = 0.007 compared to controls. ^jP < 0.001 compared to controls. ^kP = 0.002 compared to CS and ^lP < 0.001 compared to controls. ^mP = 0.006 compared to CS and ⁿP < 0.001 compared to controls. ^oP = 0.014 compared to controls. ^pP < 0.001 and ^qP = 0.001 compared to controls. ^rP = 0.010 compared to CS and ^sP < 0.001 compared to controls

ISSN: 1471-230X