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Table 1 Composition of custom MCS and MCD formulas

From: Differential hepatotoxicity of dietary and DNL-derived palmitate in the methionine-choline-deficient model of steatohepatitis

  MCS MCD
  Starch-oleate Starch-palmitate Sucrose-oleate Sucrose-palmitate Starch-oleate Starch-palmitate Sucrose-oleate Sucrose-palmitate
Protein (g/kg)
L-arginine (free base) 6.3 6.3 6.3 6.3 6.3 6.3 6.3 6.3
L-histidine (free base) 4.5 4.5 4.5 4.5 4.5 4.5 4.5 4.5
L-lysine 16.1 16.1 16.1 16.1 16.1 16.1 16.1 16.1
L-tyrosine 9.2 9.2 9.2 9.2 9.2 9.2 9.2 9.2
L-tryptophan 2.1 2.1 2.1 2.1 2.1 2.1 2.1 2.1
L-phenylalanine 8.7 8.7 8.7 8.7 8.7 8.7 8.7 8.7
L-cysteine 3.7 3.7 3.7 3.7 3.7 3.7 3.7 3.7
L-threonine 6.6 6.6 6.6 6.6 6.6 6.6 6.6 6.6
L-leucine 15.3 15.3 15.3 15.3 15.3 15.3 15.3 15.3
L-isoleucine 8.4 8.4 8.4 8.4 8.4 8.4 8.4 8.4
L-valine 9.9 9.9 9.9 9.9 9.9 9.9 9.9 9.9
Glycine 3.1 3.1 3.1 3.1 3.1 3.1 3.1 3.1
L-proline 20.4 20.4 20.4 20.4 20.4 20.4 20.4 20.4
L-glutamic acid 36.2 36.2 36.2 36.2 36.2 36.2 36.2 36.2
L-alanine 4.5 4.5 4.5 4.5 4.5 4.5 4.5 4.5
L-aspartic acid 11.3 11.3 11.3 11.3 11.3 11.3 11.3 11.3
L-serine 9.4 9.4 9.4 9.4 9.4 9.4 9.4 9.4
Carbohydrate (g/kg)
Cornstarch 587.9 587.9 0.0 0.0 591.9 591.9 0.0 0.0
Dyetrose 50.0 50.0 50.0 50.0 50.0 50.0 50.0 50.0
Sucrose 0.0 0.0 587.9 587.9 0.0 0.0 591.9 591.9
Cellulose 30.0 30.0 30.0 30.0 30.0 30.0 30.0 30.0
Fat (g/kg)
Tripalmitin 0.0 100.0 0.0 100.0 0.0 100.0 0.0 100.0
High-oleate (85 %) sunflower oil 100.0 0.0 100.0 0.0 100.0 0.0 100.0 0.0
Methionine and choline (g/kg)
L-methionine 2.0 2.0 2.0 2.0 0.0 0.0 0.0 0.0
Choline chloride 2.0 2.0 2.0 2.0 0.0 0.0 0.0 0.0
Additives (g/kg)
Salt mix #210030 35.0 35.0 35.0 35.0 35.0 35.0 35.0 35.0
Sodium bicarbonate 7.4 7.4 7.4 7.4 7.4 7.4 7.4 7.4
Vitamin Mix #310025 10.0 10.0 10.0 10.0 10.0 10.0 10.0 10.0
Total (g/kg) 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0 1000.0
Protein 18 % 18 % 18 % 18 % 18 % 18 % 18 % 18 %
CHO 64 % 64 % 64 % 64 % 64 % 64 % 64 % 64 %
Fat 10 % 10 % 10 % 10 % 10 % 10 % 10 % 10 %
Fiber 3 % 3 % 3 % 3 % 3 % 3 % 3 % 3 %