Variable | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
Hazard ratio (95Â % CI) | p-value | Hazard ratio (95Â % CI) | p-value | |
Age | 0.981 (0.958–1.004) | 0.112 |  |  |
Male gender | 2.046 (0.902–4.639) | 0.087 |  |  |
Etiology of liver cirrhosis | Â | Â | Â | Â |
  Alcoholic | 1.188 (0.577–2.455) | 0.641 |  |  |
  Viral hepatitis | 1.023 (0.722–1.488) | 0.887 |  |  |
  Cryptogenic | 0.713 (0.366 –1.392) | 0.322 |  |  |
Decompensated cirrhosis | 2.112 (1.014–4.402) | 0.046 | 1.259 (0.497–3.188) | 0.627 |
Rockall score | 1.638 (1.327–2.022) | <0.001 | 1.884 (1.477–2.404) | <0.001 |
MELD score | 1.049 (1.007–1.093) | 0.023 | 0.945 (0.875–1.020) | 0.417 |
Child-Pugh score | 1.321 (1.126–1.548) | 0.001 | 1.252 (0.915–1.712) | 0.163 |
Other comorbidities | Â | Â | Â | Â |
  Diabetes mellitus | 1.163 (0.825–1.639) | 0.388 |  |  |
  Hypertension | 0.826 (0.437–1.562) | 0.555 |  |  |
  CVD | 1.656 (0.396–6.924) | 0.490 |  |  |
  Stroke | 0.830 (0.194–3.542) | 0.801 |  |  |
  ESRD | 1.462 (0.445–4.808) | 0.532 |  |  |
  COPD | 0.495 (0.145–1.683) | 0.260 |  |  |
Use of NSAID or aspirin | 1.381 (0.765–2.493) | 0.284 |  |  |
Smoking | 1.040 (0.739–1.465) | 0.820 |  |  |
Active alcoholism | 1.453 (0.771–2.739) | 0.248 |  |  |
WBC (109/l) | 1 | 0.737 | Â | Â |
Hb (g/dl) | 0.941 (0.809–1.095) | 0.431 |  |  |
PLT (109/l) | 0.997 (0.992–1.002) | 0.211 |  |  |
PT (second) | 1.355 (0.823–2.232) | 0.232 |  |  |
Creatinine (mg/dl) | 1.003 (0.857–1.174) | 0.972 |  |  |
Albumin (g/l) | 0.906 (0.555–1.479) | 0.692 |  |  |
Total bilirubin | 1.056 (1.004–1.111) | 0.033 | 0.987 (0.916–1.063) | 0.731 |
Blood units transfused | 0.989 (0.961–1.018) | 0.468 |  |  |
Hypovolemic shock on admission | 1.184 (0.420–3.341) | 0.750 |  |  |
High risk bleeding stigmata at ulcer base | 1.103 (0.407–2.989) | 0.848 |  |  |
Time (h), bleeding to endoscopic treatment | 0.972 (0.936–1.010) | 0.143 |  |  |
Combined treatment of endoscopic hemostasis | 0.966 (0.485–1.926) | 0.922 |  |  |
Bacterial infection | 1.770 (0.945–3.318) | 0.075 |  |  |
Recurrent bleeding | 2.412 (1.292–4.501) | 0.006 | 2.796 (1.473–5.306) | 0.002 |
Antibiotic prophylaxis | 0.582 (0.293–1.151) | 0.121 |  |  |