Figure 4From: The earliest trough concentration predicts the dose of tacrolimus required for remission induction therapy in ulcerative colitis patientsThe algorithm based on the earliest trough concentration. If a patient with body weight of 60 kg started tacrolimus therapy with 6 mg/day, and the trough concentration measured 2 or 3 days after initiation was < 6 ng/mL, the dose should be increased to 12 mg/day. On the other hand, if the trough concentration measured 2 or 3 days after initiation was > 6 ng/mL, the increase of the dose should be minimizedBack to article page