|
Variable
|
Parameter estimate
|
SE of estimate
|
Risk ratio (95%CI)
|
Pvalue
|
|---|
|
Demographics
| | | | |
|
Age (yrs)
|
0.011
|
0.016
|
1.011(0.981-1.043)
|
0.465
|
|
Gender (F/M)
|
0.532
|
0.392
|
1.702(0.790-3.668)
|
0.174
|
|
Varices (−/+)
|
1.490
|
0.381
|
4.438(2.101-9.373)
|
<0.001*
|
|
Variceal rupture (−/+)
|
1.496
|
0.493
|
4.463(1.697-11.739)
|
0.002*
|
|
IL-6 (pg/mL)
|
0.015
|
0.007
|
1.015(1.002-1.028)
|
0.024*
|
|
IL-27 (pg/mL)
|
0.000
|
0.000
|
1.000(0.999-1.000)
|
0.204
|
|
TNF-α (pg/mL)
|
−0.001
|
0.001
|
0.999(0.996-1.002)
|
0.401
|
|
VEGF (pg/mL)
|
0.034
|
0.013
|
1.034(1.009-1.060)
|
0.007*
|
|
AST (IU/L)
|
0.008
|
0.003
|
1.008(1.003-1.013)
|
0.003*
|
|
ALT (IU/L)
|
0.002
|
0.002
|
1.002(0.998-1.007)
|
0.337
|
|
Albumin (g/dL)
|
−2.413
|
0.444
|
0.090(0.038-0.214)
|
<0.001*
|
|
Bilirubin (mg/dL)
|
0.455
|
0.132
|
1.576(1.216-2.042)
|
0.001*
|
|
Cr (mg/dL)
|
−0.014
|
0.132
|
0.986(0.761-1.278
|
0.914
|
|
INR
|
5.763
|
1.359
|
318.386(22.17-4572.329)
|
<0.001*
|
|
Platelet (103/uL)
|
0.001
|
0.002
|
1.001(0.997-1.006)
|
0.576
|
|
AFP (ng/mL)
|
0.000
|
0.000
|
1.000(1.000-1.000)
|
0.001*
|
|
Cirrhosis (−/+)
|
1.131
|
0.422
|
3.10(1.357-7.083)
|
0.007*
|
|
BCLC staging
|
2.394
|
0.411
|
10.958(4.897-24.522)
|
<0.001*
|
- (N = 147) *p < 0.05 defined as statistically significant.
