IL-6, through p-STAT3 rather than p-STAT1, activates hepatocarcinogenesis and affects survival of hepatocellular carcinoma patients: a cohort study

Table 2 Correlations between IL-6, IL-27, TNF-α, and VEGF with biochemical data in HCC patients

	IL-6		IL-27		TNF-α		VEGF
	γ	P	γ	P	γ	P	Γ	P
Age (years)	0.137	0.106	−0.016	0.855	−0.013	0.882	−0.078	0.363
Sex (F/M)	0.057	0.504	−0.052	0.538	−0.215	0.011*	0.023	0.788
Varices (−/+)	0.155	0.067	0.024	0.775	0.058	0.495	0.152	0.075
Variceal bleeding (−/+)	0.135	0.112	0.042	0.625	0.215	0.011*	0.154	0.071
Albumin (g/dL)	−0.383	<0.001*	−0.098	0.253	−0.031	0.717	−0.175	0.041*
Bilirubin (mg/dL)	0.280	0.001*	0.046	0.590	0.161	0.060	−0.112	0.175
Creatinine (mg/dL)	0.181	0.032*	−0.037	0.663	0.022	0.792	−0.074	0.391
AST (IU/L)	0.212	0.016*	0.112	0.208	0.092	0.300	0.020	0.819
ALT (IU/L)	−0.087	0.305	0.083	0.329	0.087	0.305	−0.084	0.325
INR	0.299	<0.001*	−0.064	0.460	−0.095	0.269	0.160	0.063
Platelet (10 ³ /uL)	0.036	0.671	0.043	0.619	0.016	0.857	0.002	0.985
AFP (ng/mL)	0.261	0.002*	0.002	0.977	0.120	0.157	0.123	0.152
TNM Staging	0.370	<0.001*	−0.109	0.200	−0.052	0.539	0.059	0.491
BCLC Staging	0.471	<0.001*	−0.028	0.739	0.035	0.682	0.158	0.065

ISSN: 1471-230X