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Table 2 Correlations between IL-6, IL-27, TNF-α, and VEGF with biochemical data in HCC patients

From: IL-6, through p-STAT3 rather than p-STAT1, activates hepatocarcinogenesis and affects survival of hepatocellular carcinoma patients: a cohort study

  IL-6 IL-27 TNF-α VEGF
  γ P γ P γ P Γ P
Age (years) 0.137 0.106 −0.016 0.855 −0.013 0.882 −0.078 0.363
Sex (F/M) 0.057 0.504 −0.052 0.538 −0.215 0.011* 0.023 0.788
Varices (−/+) 0.155 0.067 0.024 0.775 0.058 0.495 0.152 0.075
Variceal bleeding (−/+) 0.135 0.112 0.042 0.625 0.215 0.011* 0.154 0.071
Albumin (g/dL) −0.383 <0.001* −0.098 0.253 −0.031 0.717 −0.175 0.041*
Bilirubin (mg/dL) 0.280 0.001* 0.046 0.590 0.161 0.060 −0.112 0.175
Creatinine (mg/dL) 0.181 0.032* −0.037 0.663 0.022 0.792 −0.074 0.391
AST (IU/L) 0.212 0.016* 0.112 0.208 0.092 0.300 0.020 0.819
ALT (IU/L) −0.087 0.305 0.083 0.329 0.087 0.305 −0.084 0.325
INR 0.299 <0.001* −0.064 0.460 −0.095 0.269 0.160 0.063
Platelet (10 3 /uL) 0.036 0.671 0.043 0.619 0.016 0.857 0.002 0.985
AFP (ng/mL) 0.261 0.002* 0.002 0.977 0.120 0.157 0.123 0.152
TNM Staging 0.370 <0.001* −0.109 0.200 −0.052 0.539 0.059 0.491
BCLC Staging 0.471 <0.001* −0.028 0.739 0.035 0.682 0.158 0.065
  1. (N = 147) *p < 0.05 defined as significant