TY - STD TI - Garcia M, Jemal A, Ward EM, Center MM, Hao Y, Siegel RL, Thun MJ. Global Cancer Facts and Figures 2007 [http://www.cancer.org] UR - http://www.cancer.org ID - ref1 ER - TY - JOUR AU - Lee, W. M. PY - 1997 DA - 1997// TI - Hepatitis B virus infection JO - N Engl J Med VL - 337 UR - https://doi.org/10.1056/NEJM199712113372406 DO - 10.1056/NEJM199712113372406 ID - Lee1997 ER - TY - JOUR AU - Lauer, G. M. AU - Walker, B. D. PY - 2001 DA - 2001// TI - Hepatitis C virus infection JO - N Engl J Med VL - 345 UR - https://doi.org/10.1056/NEJM200107053450107 DO - 10.1056/NEJM200107053450107 ID - Lauer2001 ER - TY - JOUR AU - Bosch, F. X. AU - Ribes, J. AU - Díaz, M. AU - Cléries, R. PY - 2004 DA - 2004// TI - Primary liver cancer: worldwide incidence and trends JO - Gastroenterology VL - 127 UR - https://doi.org/10.1053/j.gastro.2004.09.011 DO - 10.1053/j.gastro.2004.09.011 ID - Bosch2004 ER - TY - JOUR AU - Singal, A. AU - Volk, M. L. AU - Waljee, A. AU - Salgia, R. AU - Higgins, P. AU - Rogers, M. A. PY - 2009 DA - 2009// TI - Meta-analysis: surveillance with ultrasound for early-stage hepatocellular carcinoma in patients with cirrhosis JO - Aliment Pharmacol Ther VL - 30 UR - https://doi.org/10.1111/j.1365-2036.2009.04014.x DO - 10.1111/j.1365-2036.2009.04014.x ID - Singal2009 ER - TY - JOUR AU - Llovet, J. M. PY - 2005 DA - 2005// TI - Updated treatment approach to hepatocellular carcinoma JO - J Gastroenterol VL - 40 UR - https://doi.org/10.1007/s00535-005-1566-3 DO - 10.1007/s00535-005-1566-3 ID - Llovet2005 ER - TY - JOUR AU - Semela, D. AU - Dufour, J. F. PY - 2004 DA - 2004// TI - Angiogenesis and hepatocellular carcinoma JO - J Hepatol VL - 41 UR - https://doi.org/10.1016/j.jhep.2004.09.006 DO - 10.1016/j.jhep.2004.09.006 ID - Semela2004 ER - TY - JOUR AU - Villanueva, A. AU - Hoshida, Y. AU - Toffanin, S. AU - Lachenmayer, A. AU - Alsinet, C. AU - Savic, R. PY - 2010 DA - 2010// TI - New strategies in hepatocellular carcinoma: genomic prognostic markers JO - Clin Cancer Res VL - 16 UR - https://doi.org/10.1158/1078-0432.CCR-09-1811 DO - 10.1158/1078-0432.CCR-09-1811 ID - Villanueva2010 ER - TY - JOUR AU - Llovet, J. M. AU - Pena, C. E. AU - Lathia, C. D. AU - Shan, M. AU - Meinhardt, G. AU - Bruix, J. PY - 2012 DA - 2012// TI - Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma JO - Clin Cancer Res VL - 18 UR - https://doi.org/10.1158/1078-0432.CCR-11-2175 DO - 10.1158/1078-0432.CCR-11-2175 ID - Llovet2012 ER - TY - JOUR AU - Llovet, J. M. AU - Ricci, S. AU - Mazzaferro, V. AU - Hilgard, P. AU - Gane, E. AU - Blanc, J. F. PY - 2008 DA - 2008// TI - Sorafenib in advanced hepatocellular carcinoma JO - N Engl J Med VL - 359 UR - https://doi.org/10.1056/NEJMoa0708857 DO - 10.1056/NEJMoa0708857 ID - Llovet2008 ER - TY - JOUR AU - Cheng, A. L. AU - Kang, Y. K. AU - Chen, Z. AU - Tsao, C. J. AU - Qin, S. AU - Kim, J. S. PY - 2009 DA - 2009// TI - Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial JO - Lancet Oncol VL - 10 UR - https://doi.org/10.1016/S1470-2045(08)70285-7 DO - 10.1016/S1470-2045(08)70285-7 ID - Cheng2009 ER - TY - JOUR AU - Johnson, C. AU - Han, Y. AU - Hughart, N. AU - McCarra, J. AU - Alpini, G. AU - Meng, F. PY - 2012 DA - 2012// TI - Interleukin-6 and its receptor, key players in hepatobiliary inflammation and cancer JO - Transl Gastrointest Cancer VL - 1 ID - Johnson2012 ER - TY - JOUR AU - Trinchieri, G. AU - Pflanz, S. AU - Kastelein, R. A. PY - 2003 DA - 2003// TI - The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses JO - Immunity VL - 19 UR - https://doi.org/10.1016/S1074-7613(03)00296-6 DO - 10.1016/S1074-7613(03)00296-6 ID - Trinchieri2003 ER - TY - STD TI - Das L, Vinayak M. Long term effect of curcumin down regulates expression of TNF-α and IL-6 via modulation of ETS and NF-κB transcription factor in liver of lymphoma bearing mice. Leuk Lymphoma 2014 Feb 4. [Epub ahead of print] ID - ref14 ER - TY - JOUR AU - Ferrara, N. AU - Gerber, H. P. AU - LeCouter, J. PY - 2003 DA - 2003// TI - The biology of VEGF and its receptors JO - Nat Med VL - 9 UR - https://doi.org/10.1038/nm0603-669 DO - 10.1038/nm0603-669 ID - Ferrara2003 ER - TY - JOUR AU - Guo, Y. AU - Xu, F. AU - Lu, T. J. AU - Duan, Z. F. AU - Zhang, Z. PY - 2012 DA - 2012// TI - Interleukin-6 signaling pathway in targeted therapy for cancer JO - Cancer Treat Rev VL - 38 UR - https://doi.org/10.1016/j.ctrv.2012.04.007 DO - 10.1016/j.ctrv.2012.04.007 ID - Guo2012 ER - TY - JOUR AU - Cressman, D. E. AU - Greenbaum, L. E. AU - DeAngelis, R. A. AU - Ciliberto, G. AU - Furth, E. E. AU - Poli, V. PY - 1996 DA - 1996// TI - Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice JO - Science VL - 274 UR - https://doi.org/10.1126/science.274.5291.1379 DO - 10.1126/science.274.5291.1379 ID - Cressman1996 ER - TY - JOUR AU - Kao, J. T. AU - Lai, H. C. AU - Tsai, S. M. AU - Lin, P. C. AU - Chuang, P. H. AU - Yu, C. J. PY - 2012 DA - 2012// TI - Rather than interleukin-27, interleukin-6 expresses positive correlation with liver severity in naïve hepatitis B infection patients JO - Liver Int VL - 32 UR - https://doi.org/10.1111/j.1478-3231.2011.02742.x DO - 10.1111/j.1478-3231.2011.02742.x ID - Kao2012 ER - TY - JOUR AU - Li, K. AU - Li, N. L. AU - Wei, D. AU - Pfeffer, S. R. AU - Fan, M. AU - Pfeffer, L. M. PY - 2012 DA - 2012// TI - Activation of chemokine and inflammatory cytokine response in hepatitis C virus-infected hepatocytes depends on toll-like receptor 3 sensing of hepatitis C virus double-stranded RNA intermediates JO - Hepatology VL - 55 UR - https://doi.org/10.1002/hep.24763 DO - 10.1002/hep.24763 ID - Li2012 ER - TY - JOUR AU - Bender, H. AU - Wiesinger, M. Y. AU - Nordhoff, C. AU - Schoenherr, C. AU - Haan, C. AU - Ludwig, S. PY - 2009 DA - 2009// TI - Interleukin-27 displays interferon-gamma-like functions in human hepatoma cells and hepatocytes JO - Hepatology VL - 50 UR - https://doi.org/10.1002/hep.22988 DO - 10.1002/hep.22988 ID - Bender2009 ER - TY - JOUR AU - Shimizu, M. AU - Shimamura, M. AU - Owaki, T. AU - Asakawa, M. AU - Fujita, K. AU - Kudo, M. PY - 2006 DA - 2006// TI - Antiangiogenic and antitumor activities of IL-27 JO - J Immunol VL - 176 UR - https://doi.org/10.4049/jimmunol.176.12.7317 DO - 10.4049/jimmunol.176.12.7317 ID - Shimizu2006 ER - TY - JOUR AU - Moncada, S. AU - Higgs, A. PY - 1993 DA - 1993// TI - The L-arginine-nitric oxide pathway JO - N Engl J Med VL - 329 UR - https://doi.org/10.1056/NEJM199312303292706 DO - 10.1056/NEJM199312303292706 ID - Moncada1993 ER - TY - JOUR AU - Mookerjee, R. P. AU - Sen, S. AU - Davies, N. A. AU - Hodges, S. J. AU - Williams, R. AU - Jalan, R. PY - 2003 DA - 2003// TI - Tumour necrosis factor is an important mediator of portal and systemic haemodynamic derangements in alcoholic hepatitis JO - Gut VL - 52 UR - https://doi.org/10.1136/gut.52.8.1182 DO - 10.1136/gut.52.8.1182 ID - Mookerjee2003 ER - TY - JOUR AU - Jiao, S. F. AU - Sun, K. AU - Chen, X. J. AU - Zhao, X. AU - Cai, N. AU - Liu, Y. J. PY - 2014 DA - 2014// TI - Inhibition of tumor necrosis factor alpha reduces the outgrowth of hepatic micrometastasis of colorectal tumors in mouse model of liver ischemia-reperfusion injury JO - J Biomed Sci VL - 21 UR - https://doi.org/10.1186/1423-0127-21-1 DO - 10.1186/1423-0127-21-1 ID - Jiao2014 ER - TY - JOUR AU - Leung, D. W. AU - Cachiane, G. AU - Kuang, W. J. AU - Goeddel, D. V. AU - Ferrara, N. PY - 1989 DA - 1989// TI - Vascular endothelial growth factor is a secreted angiogenic mitogen JO - Science VL - 246 UR - https://doi.org/10.1126/science.2479986 DO - 10.1126/science.2479986 ID - Leung1989 ER - TY - JOUR AU - Suzuki, K. AU - Hayashi, N. AU - Miyamoto, Y. AU - Yamamoto, M. AU - Ohkawa, K. AU - Ito, Y. PY - 1996 DA - 1996// TI - Expression of vascular permeability factor/vascular endothelial growth factor in human hepatocellular carcinoma JO - Cancer Res VL - 56 ID - Suzuki1996 ER - TY - JOUR AU - Wilhelm, S. M. AU - Carter, C. AU - Tang, L. AU - Wilkie, D. AU - McNabola, A. AU - Rong, H. PY - 2004 DA - 2004// TI - BAY 43–9006 exhibits broad spectrum oral antitumor activity and targets the Raf/Mek/Erk pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis JO - Cancer Res VL - 64 UR - https://doi.org/10.1158/0008-5472.CAN-04-1443 DO - 10.1158/0008-5472.CAN-04-1443 ID - Wilhelm2004 ER - TY - JOUR AU - Ribatti, D. AU - Vacca, A. AU - Nico, B. AU - Sansonno, D. AU - Dammacco, F. PY - 2006 DA - 2006// TI - Angiogenesis and anti-angiogenesis in hepatocellular carcinoma JO - Cancer Treat Rev VL - 32 UR - https://doi.org/10.1016/j.ctrv.2006.06.002 DO - 10.1016/j.ctrv.2006.06.002 ID - Ribatti2006 ER - TY - JOUR AU - Gao, B. AU - Wang, H. AU - Lafdil, F. AU - Feng, D. PY - 2012 DA - 2012// TI - STAT proteins-Key regulators of anti-viral responses, inflammation, and tumorigenesis in the liver JO - J Hepatol VL - 57 UR - https://doi.org/10.1016/j.jhep.2012.01.029 DO - 10.1016/j.jhep.2012.01.029 ID - Gao2012 ER - TY - JOUR AU - Slattery, M. L. AU - Lundgreen, A. AU - Kadlubar, S. A. AU - Bondurant, K. L. AU - Wolff, R. K. PY - 2013 DA - 2013// TI - JAK/STAT/SOCS-signaling pathway and colon and rectal cancer JO - Mol Cancinog VL - 52 UR - https://doi.org/10.1002/mc.21841 DO - 10.1002/mc.21841 ID - Slattery2013 ER - TY - JOUR AU - Chen, Y. AU - Lan, Q. AU - Zheng, T. AU - Zhao, N. AU - Holford, T. R. AU - Lerro, C. PY - 2013 DA - 2013// TI - Polymorphisms in JAK/STAT signaling pathway genes and risk of non-Hodgkin lymphoma JO - Leuk Res VL - 37 UR - https://doi.org/10.1016/j.leukres.2013.05.003 DO - 10.1016/j.leukres.2013.05.003 ID - Chen2013 ER - TY - STD TI - Fazilaty H, Mehdipour P. Genetics of breast cancer bone metastasis: a sequential multistep pattern. Clin Exp Metastasis 2014 Feb 4. [Epub ahead of print] ID - ref32 ER - TY - JOUR AU - Dokduang, H. AU - Techasen, A. AU - Namwat, N. AU - Khuntikeo, N. AU - Pairojkul, C. AU - Murakami, Y. PY - 2014 DA - 2014// TI - STATs profiling reveals predominantly-activated STAT3 in cholangiocarcinoma genesis and progression JO - J Hepatobiliary Pancreat Sci VL - 21 UR - https://doi.org/10.1002/jhbp.131 DO - 10.1002/jhbp.131 ID - Dokduang2014 ER - TY - JOUR AU - Wei, L. H. AU - Kuo, M. L. AU - Chen, C. A. AU - Chou, C. H. AU - Lai, K. B. AU - Lee, C. N. PY - 2003 DA - 2003// TI - Interleukin-6 promotes cervical tumor growth by VEGF dependent angiogenesis via a STAT3 pathway JO - Oncogene VL - 22 UR - https://doi.org/10.1038/sj.onc.1206226 DO - 10.1038/sj.onc.1206226 ID - Wei2003 ER - TY - JOUR AU - Webb, N. J. AU - Bottomley, M. J. AU - Watson, C. J. AU - Brenchley, P. E. PY - 1998 DA - 1998// TI - Vascular endothelial growth factor (VEGF) is released from platelets during blood clotting: implications for measurement of circulating VEGF levels in clinical disease JO - Clin Sci (Lond) VL - 94 UR - https://doi.org/10.1042/cs0940395 DO - 10.1042/cs0940395 ID - Webb1998 ER -